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4TIM
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CRYSTALLOGRAPHIC AND MOLECULAR MODELING STUDIES ON TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE: A CRITICAL ASSESSMENT OF THE PREDICTED AND OBSERVED STRUCTURES OF THE COMPLEX WITH 2-PHOSPHOGLYCERATE
Descriptor: 2-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Nobel, M.E.M, Wierenga, R.K, Hol, W.G.J.
Deposit date:1991-04-11
Release date:1992-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate.
J.Med.Chem., 34, 1991
1HG3
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Crystal structure of tetrameric TIM from Pyrococcus woesei.
Descriptor: 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Walden, H, Bell, G.S, Russell, R.J.M, Siebers, B, Hensel, R, Taylor, G.L.
Deposit date:2000-12-12
Release date:2001-03-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Tiny Tim: A Small, Tetrameric, Hyperthermostable Triosephosphate Isomerase
J.Mol.Biol., 306, 2001
3KRS
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Structure of Triosephosphate Isomerase from Cryptosporidium Parvum at 1.55A Resolution
Descriptor: SODIUM ION, Triosephosphate isomerase, UNKNOWN ATOM OR ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-11-19
Release date:2009-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of triosephosphate isomerase from Cryptosporidium parvum.
Acta Crystallogr.,Sect.F, 67, 2011
1HTI
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN TRIOSEPHOSPHATE ISOMERASE AT 2.8 ANGSTROMS RESOLUTION. TRIOSEPHOSPHATE ISOMERASE RELATED HUMAN GENETIC DISORDERS AND COMPARISON WITH THE TRYPANOSOMAL ENZYME
Descriptor: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Mande, S.C, Hol, W.G.J.
Deposit date:1994-10-12
Release date:1995-01-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.
Protein Sci., 3, 1994
4FF7
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Structure of C126S mutant of Saccharomyces cerevisiae triosephosphate isomerase
Descriptor: 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, PHOSPHATE ION, ...
Authors:Rodriguez-Romero, A, Hernandez-Santoyo, A.
Deposit date:2012-05-31
Release date:2012-08-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Effects of a buried cysteine-to-serine mutation on yeast triosephosphate isomerase structure and stability.
Int J Mol Sci, 13, 2012
4G1K
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Crystal structure of triosephosphate isomerase from Burkholderia thailandensis
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-07-10
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4POC
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BU of 4poc by Molmil
Structure of Triosephosphate Isomerase Wild Type human enzyme.
Descriptor: BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P.
Deposit date:2014-02-25
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
4PCF
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Structure-based protein engineering of a monomeric triosephosphate isomerase towards changing substrate specificity
Descriptor: Ma18-TIM
Authors:Krause, M, Neubauer, P, Wierenga, R.K.
Deposit date:2014-04-15
Release date:2015-04-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity.
Acta Crystallogr.,Sect.F, 72, 2016
4HHP
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Crystal structure of triosephosphate isomerase from trypanosoma cruzi, mutant e105d
Descriptor: GLYCEROL, SULFATE ION, Triosephosphate isomerase, ...
Authors:Hernandez-Santoyo, A, Aguirre-Fuentes, Y, Torres-Larios, A, Gomez-Puyou, A, De Gomez-Puyou, M.T.
Deposit date:2012-10-10
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Different contribution of conserved amino acids to the global properties of triosephosphate isomerases.
Proteins, 82, 2014
2Y70
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CRYSTALLOGRAPHIC STRUCTURE OF GM23, MUTANT G89D, AN EXAMPLE OF CATALYTIC MIGRATION FROM TIM TO THIAMIN PHOSPHATE SYNTHASE.
Descriptor: ACETATE ION, SULFATE ION, TRIOSE-PHOSPHATE ISOMERASE
Authors:Saab-Rincon, G, Olvera, L, Olvera, M, Rudino-Pinera, E, Soberon, X, Morett, E.
Deposit date:2011-01-27
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolutionary Walk between (Beta/Alpha)(8) Barrels: Catalytic Migration from Triosephosphate Isomerase to Thiamin Phosphate Synthase.
J.Mol.Biol., 416, 2012
4POD
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BU of 4pod by Molmil
Structure of Triosephosphate Isomerase I170V mutant human enzyme.
Descriptor: BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P.
Deposit date:2014-02-25
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
5EYW
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BU of 5eyw by Molmil
Crystal structure of Litopenaeus vannamei triosephosphate isomerase complexed with 2-Phosphoglycolic acid
Descriptor: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase
Authors:Carrasco-Miranda, J.S, Lopez-Zavala, A.A, Brieba, L.G, Rudino-Pinera, E, Sotelo-Mundo, R.R.
Deposit date:2015-11-25
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights from a novel invertebrate triosephosphate isomerase from Litopenaeus vannamei.
Biochim.Biophys.Acta, 1864, 2016
4IOT
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BU of 4iot by Molmil
High-resolution Structure of Triosephosphate isomerase from E. coli
Descriptor: SULFATE ION, Triosephosphate isomerase
Authors:Vinaik, R, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2013-01-08
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Triosephosphate isomerase is a common crystallization contaminant of soluble His-tagged proteins produced in Escherichia coli.
Acta Crystallogr.,Sect.F, 69, 2013
2YPI
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BU of 2ypi by Molmil
CRYSTALLOGRAPHIC ANALYSIS OF THE COMPLEX BETWEEN TRIOSEPHOSPHATE ISOMERASE AND 2-PHOSPHOGLYCOLATE AT 2.5-ANGSTROMS RESOLUTION. IMPLICATIONS FOR CATALYSIS
Descriptor: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Lolis, E, Petsko, G.A.
Deposit date:1990-01-12
Release date:1991-01-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-A resolution: implications for catalysis.
Biochemistry, 29, 1990
2Y6Z
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BU of 2y6z by Molmil
Crystallographic structure of GM23 an example of Catalytic migration from TIM to thiamin phosphate synthase.
Descriptor: PYROPHOSPHATE 2-, THIAMIN PHOSPHATE, TRIOSE-PHOSPHATE ISOMERASE
Authors:Saab-Rincon, G, Olvera, L, Olvera, M, Rudino-Pinera, E, Soberon, X, Morett, E.
Deposit date:2011-01-27
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Evolutionary Walk between (Beta/Alpha)(8) Barrels: Catalytic Migration from Triosephosphate Isomerase to Thiamin Phosphate Synthase.
J.Mol.Biol., 416, 2012
5GV4
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BU of 5gv4 by Molmil
Y74COX MUTANT OF PLASMODIUM FALCIPARUM TRIOSEPHOSPHATE ISOMERASE
Descriptor: 1,2-ETHANEDIOL, 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase
Authors:Pareek, V, Balaram, P, Murthy, M.R.N.
Deposit date:2016-09-01
Release date:2017-09-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Y74COX MUTANT OF PLASMODIUM FALCIPARUM TRIOSEPHOSPHATE ISOMERASE
To Be Published
4JEQ
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Different Contribution of Conserved Amino Acids to the Global Properties of Homologous Enzymes
Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIOSEPHOSPHATE ISOMERASE, ...
Authors:Hernandez-Santoyo, A, Aguirre-Fuentes, Y, Torres-Larios, A, Gomez-Puyou, A, De Gomez-Puyou, M.T.
Deposit date:2013-02-27
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Different contribution of conserved amino acids to the global properties of triosephosphate isomerases.
Proteins, 82, 2014
5GZP
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BU of 5gzp by Molmil
Y74COX MUTANT OF PLASMODIUM FALCIPARUM TRIOSEPHOSPHATE ISOMERASE
Descriptor: 1,2-ETHANEDIOL, 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase
Authors:Pareek, V, Balaram, P, Murthy, M.R.N.
Deposit date:2016-09-30
Release date:2017-10-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Y74COX MUTANT OF PLASMODIUM FALCIPARUM TRIOSEPHOSPHATE ISOMERASE
To Be Published
5TIM
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BU of 5tim by Molmil
REFINED 1.83 ANGSTROMS STRUCTURE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE, CRYSTALLIZED IN THE PRESENCE OF 2.4 M-AMMONIUM SULPHATE. A COMPARISON WITH THE STRUCTURE OF THE TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE-GLYCEROL-3-PHOSPHATE COMPLEX
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
Authors:Wierenga, R.K, Hol, W.G.J.
Deposit date:1991-04-23
Release date:1992-10-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex.
J.Mol.Biol., 220, 1991
6CG9
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BU of 6cg9 by Molmil
Crystal structure of Triosephosphate Isomerase from Zea mays (mexican corn)
Descriptor: ACETATE ION, GLYCEROL, Triosephosphate isomerase, ...
Authors:Romero-Romero, S, Fernandez-Velasco, D.A, Rodriguez-Romero, A.
Deposit date:2018-02-19
Release date:2018-10-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and conformational stability of the triosephosphate isomerase from Zea mays. Comparison with the chemical unfolding pathways of other eukaryotic TIMs.
Arch. Biochem. Biophys., 658, 2018
5UPR
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BU of 5upr by Molmil
X-ray structure of a putative triosephosphate isomerase from Toxoplasma gondii ME49
Descriptor: CHLORIDE ION, SULFATE ION, Triosephosphate isomerase
Authors:Filippova, E.V, Wawrzak, Z, Minasov, G, Cardona-Correa, A, Bishop, B, Anderson, W.F, Ngo, H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-02-03
Release date:2017-02-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of a putative triosephosphate isomerase from Toxoplasma gondii ME49
To Be Published
6BVE
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Triosephosphate isomerase of Synechocystis in complex with 2-Phosphoglycolic acid
Descriptor: 2-PHOSPHOGLYCOLIC ACID, SODIUM ION, Triosephosphate isomerase
Authors:Jimenez-Sandoval, P, Castro-Torres, E, Brieba, L.G.
Deposit date:2017-12-12
Release date:2018-12-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Basis for the Limited Response to Oxidative and Thiol-Conjugating Agents by Triosephosphate Isomerase From the Photosynthetic BacteriaSynechocystis.
Front Mol Biosci, 5, 2018
5UJW
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BU of 5ujw by Molmil
Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
Descriptor: 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, CITRIC ACID, ...
Authors:Chang, C, Maltseva, N, Kim, Y, Shatsman, S, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-01-19
Release date:2017-02-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
To Be Published
5ZGA
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Crystal Structure of Triosephosphate isomerase SAD deletion and N115A mutant from Opisthorchis viverrini
Descriptor: Triosephosphate isomerase
Authors:Son, J, Kim, S, Kim, S.E, Lee, H, Lee, M.R, Hwang, K.Y.
Deposit date:2018-03-08
Release date:2018-10-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini.
Sci Rep, 8, 2018
5ZG5
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Crystal Structure of Triosephosphate isomerase SADsubAAA mutant from Opisthorchis viverrini
Descriptor: Triosephosphate isomerase
Authors:Son, J, Kim, S, Kim, S.E, Lee, H, Lee, M.R, Hwang, K.Y.
Deposit date:2018-03-07
Release date:2018-10-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.597 Å)
Cite:Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini.
Sci Rep, 8, 2018

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