4JEQ

Different Contribution of Conserved Amino Acids to the Global Properties of Homologous Enzymes

Summary for 4JEQ

Related4hhp
DescriptorTRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL, SULFATE ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywordstim barrel, isomerase, disease mutation, pentose shunt, gluconeogenesis, glycolysis
Biological sourceTRYPANOSOMA CRUZI
Cellular locationGlycosome P04789
Total number of polymer chains12
Total molecular weight323232.6
Authors
Hernandez-Santoyo, A.,Aguirre-Fuentes, Y.,Torres-Larios, A.,Gomez-Puyou, A.,De Gomez-Puyou, M.T. (deposition date: 2013-02-27, release date: 2013-10-02, Last modification date: 2014-02-05)
Primary citation
Aguirre, Y.,Cabrera, N.,Aguirre, B.,Perez-Montfort, R.,Hernandez-Santoyo, A.,Reyes-Vivas, H.,Enriquez-Flores, S.,de Gomez-Puyou, M.T.,Gomez-Puyou, A.,Sanchez-Ruiz, J.M.,Costas, M.
Different contribution of conserved amino acids to the global properties of triosephosphate isomerases.
Proteins, 82:323-335, 2014
PubMed: 23966267 (PDB entries with the same primary citation)
DOI: 10.1002/prot.24398
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.303 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26370 4.2% 6.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171313
PDB entries from 2020-11-18