4JEQ

Different Contribution of Conserved Amino Acids to the Global Properties of Homologous Enzymes

Summary for 4JEQ

Entry DOI	10.2210/pdb4jeq/pdb
Related	4hhp
Descriptor	TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL, SULFATE ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywords	tim barrel, isomerase, disease mutation, pentose shunt, gluconeogenesis, glycolysis
Biological source	TRYPANOSOMA CRUZI
Cellular location	Glycosome: P04789
Total number of polymer chains	12
Total formula weight	323232.60
Authors	Hernandez-Santoyo, A.,Aguirre-Fuentes, Y.,Torres-Larios, A.,Gomez-Puyou, A.,De Gomez-Puyou, M.T. (deposition date: 2013-02-27, release date: 2013-10-02, Last modification date: 2023-09-20)
Primary citation	Aguirre, Y.,Cabrera, N.,Aguirre, B.,Perez-Montfort, R.,Hernandez-Santoyo, A.,Reyes-Vivas, H.,Enriquez-Flores, S.,de Gomez-Puyou, M.T.,Gomez-Puyou, A.,Sanchez-Ruiz, J.M.,Costas, M. Different contribution of conserved amino acids to the global properties of triosephosphate isomerases. Proteins, 82:323-335, 2014 Cited by PubMed: 23966267 DOI: 10.1002/prot.24398 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.303 Å)

Structure validation