4HHP

Crystal structure of triosephosphate isomerase from trypanosoma cruzi, mutant e105d

Summary for 4HHP

Entry DOI	10.2210/pdb4hhp/pdb
Related	1CI1 1TCD
Descriptor	Triosephosphate isomerase, glycosomal, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywords	tim barrel, isomerase, disease mutation, pentose shunt, gluconeogenesis, glycolysis
Biological source	Trypanosoma cruzi
Cellular location	Glycosome: P52270
Total number of polymer chains	2
Total formula weight	54973.08
Authors	Hernandez-Santoyo, A.,Aguirre-Fuentes, Y.,Torres-Larios, A.,Gomez-Puyou, A.,De Gomez-Puyou, M.T. (deposition date: 2012-10-10, release date: 2013-10-16, Last modification date: 2024-02-28)
Primary citation	Aguirre, Y.,Cabrera, N.,Aguirre, B.,Perez-Montfort, R.,Hernandez-Santoyo, A.,Reyes-Vivas, H.,Enriquez-Flores, S.,de Gomez-Puyou, M.T.,Gomez-Puyou, A.,Sanchez-Ruiz, J.M.,Costas, M. Different contribution of conserved amino acids to the global properties of triosephosphate isomerases. Proteins, 82:323-335, 2014 Cited by PubMed: 23966267 DOI: 10.1002/prot.24398 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation