4POC
Structure of Triosephosphate Isomerase Wild Type human enzyme.
Summary for 4POC
Entry DOI | 10.2210/pdb4poc/pdb |
Related | 4POD |
Descriptor | Triosephosphate isomerase, POTASSIUM ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | tim alpha/beta barrel, tim barrel, isomerase, glycolytic |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 54807.99 |
Authors | Amrich, C.G.,Aslam, A.A.,Heroux, A.,VanDemark, A.P. (deposition date: 2014-02-25, release date: 2015-01-14, Last modification date: 2023-09-20) |
Primary citation | Roland, B.P.,Amrich, C.G.,Kammerer, C.J.,Stuchul, K.A.,Larsen, S.B.,Rode, S.,Aslam, A.A.,Heroux, A.,Wetzel, R.,VanDemark, A.P.,Palladino, M.J. Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. Biochim.Biophys.Acta, 1852:61-69, 2015 Cited by PubMed: 25463631DOI: 10.1016/j.bbadis.2014.10.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.601 Å) |
Structure validation
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