4PCF
Structure-based protein engineering of a monomeric triosephosphate isomerase towards changing substrate specificity
Summary for 4PCF
| Entry DOI | 10.2210/pdb4pcf/pdb |
| Related | 1AG1 1DKW 1IIG 1ML1 1MSS 1TRI 2V0T 2V5L 2VEI 2VEK 2VEL 2VEM 2VEN 3TIM 5TIM 6TIM |
| Descriptor | Ma18-TIM (2 entities in total) |
| Functional Keywords | triosephosphate isomerase, tim barrel, protein engineering, substrate specificity, isomerase |
| Biological source | Trypanosoma brucei brucei |
| Total number of polymer chains | 3 |
| Total formula weight | 77509.80 |
| Authors | Krause, M.,Neubauer, P.,Wierenga, R.K. (deposition date: 2014-04-15, release date: 2015-04-22, Last modification date: 2023-12-27) |
| Primary citation | Krause, M.,Kiema, T.R.,Neubauer, P.,Wierenga, R.K. Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity. Acta Crystallogr.,Sect.F, 72:490-499, 2016 Cited by PubMed: 27303904DOI: 10.1107/S2053230X16007548 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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