4TIM
CRYSTALLOGRAPHIC AND MOLECULAR MODELING STUDIES ON TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE: A CRITICAL ASSESSMENT OF THE PREDICTED AND OBSERVED STRUCTURES OF THE COMPLEX WITH 2-PHOSPHOGLYCERATE
Summary for 4TIM
Entry DOI | 10.2210/pdb4tim/pdb |
Descriptor | TRIOSEPHOSPHATE ISOMERASE, 2-PHOSPHOGLYCERIC ACID (3 entities in total) |
Functional Keywords | isomerase(intramolecular oxidoreductase) |
Biological source | Trypanosoma brucei brucei |
Cellular location | Glycosome: P04789 |
Total number of polymer chains | 2 |
Total formula weight | 53917.72 |
Authors | Nobel, M.E.M.,Wierenga, R.K.,Hol, W.G.J. (deposition date: 1991-04-11, release date: 1992-10-15, Last modification date: 2024-02-28) |
Primary citation | Noble, M.E.,Verlinde, C.L.,Groendijk, H.,Kalk, K.H.,Wierenga, R.K.,Hol, W.G. Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate. J.Med.Chem., 34:2709-2718, 1991 Cited by PubMed: 1895291DOI: 10.1021/jm00113a007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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