1JFF
| Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Lowe, J, Li, H, Downing, K.H, Nogales, E. | Deposit date: | 2001-06-20 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | ELECTRON CRYSTALLOGRAPHY (3.5 Å) | Cite: | Refined structure of alpha beta-tubulin at 3.5 A resolution. J.Mol.Biol., 313, 2001
|
|
3CB2
| |
6DPU
| Undecorated GMPCPP microtubule | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Zhang, R, Nogales, E. | Deposit date: | 2018-06-09 | Release date: | 2018-07-04 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Separating the effects of nucleotide and EB binding on microtubule structure. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6DPW
| Undecorated GTPgammaS microtubule | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zhang, R, Nogales, E. | Deposit date: | 2018-06-09 | Release date: | 2018-07-04 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Separating the effects of nucleotide and EB binding on microtubule structure. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5LOV
| DZ-2384 tubulin complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DZ 2384, ... | Authors: | Prota, A.E, Steinmetz, M.O, Shore, G.C, Brouhard, G, Roulston, A. | Deposit date: | 2016-08-10 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. Sci Transl Med, 8, 2016
|
|
5LXS
| Tubulin-KS-1-199-32 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Prota, A.E, Steinmetz, M.O. | Deposit date: | 2016-09-22 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis of Microtubule Stabilization by Discodermolide. Chembiochem, 18, 2017
|
|
5LP6
| Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S. | Deposit date: | 2016-08-11 | Release date: | 2016-09-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Tools for the rational design of bivalent microtubule-targeting drugs. Biochem. Biophys. Res. Commun., 479, 2016
|
|
6DPV
| Undecorated GDP microtubule | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zhang, R, Nogales, E. | Deposit date: | 2018-06-09 | Release date: | 2018-07-04 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Separating the effects of nucleotide and EB binding on microtubule structure. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
2P4N
| |
2Q1Y
| |
2Q1X
| |
6KIO
| Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT | Descriptor: | Dynein heavy chain, cytoplasmic, Tubulin alpha-1A chain, ... | Authors: | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | Deposit date: | 2019-07-19 | Release date: | 2020-03-04 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Structural basis for two-way communication between dynein and microtubules. Nat Commun, 11, 2020
|
|
3DCO
| Drosophila NOD (3DC4) and Bovine Tubulin (1JFF) Docked into the 11-Angstrom Cryo-EM Map of Nucleotide-Free NOD Complexed to the Microtubule | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Bovine Alpha Tubulin, Bovine Beta Tubulin, ... | Authors: | Sindelar, C.V, Cochran, J.C, Kull, F.J. | Deposit date: | 2008-06-04 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.), 136, 2009
|
|
8JJB
| Crystal structure of T2R-TTL-Y61 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Yang, J. | Deposit date: | 2023-05-30 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents. Eur.J.Med.Chem., 268, 2024
|
|
8JJC
| Tubulin-Y62 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(6,7-dimethoxy-3,4-dihydro-1~{H}-isoquinolin-2-yl)-6-(3-methoxyphenyl)pyrimidin-2-amine, CALCIUM ION, ... | Authors: | Yang, J. | Deposit date: | 2023-05-30 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents. Eur.J.Med.Chem., 268, 2024
|
|
3EDL
| Kinesin13-Microtubule Ring complex | Descriptor: | 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, Beta tubulin, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Tan, D, Rice, W.J, Sosa, H. | Deposit date: | 2008-09-03 | Release date: | 2009-01-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (28 Å) | Cite: | Structure of the kinesin13-microtubule ring complex. Structure, 16, 2008
|
|
6KVQ
| S. aureus FtsZ in complex with BOFP (compound 3) | Descriptor: | CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S. | Deposit date: | 2019-09-05 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Sci Rep, 9, 2019
|
|
6KPP
| BNC105 in complex with tubulin | Descriptor: | (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Wang, T, Wu, C, Pu, D. | Deposit date: | 2019-08-15 | Release date: | 2020-08-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.74524117 Å) | Cite: | Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design. Biochem.Biophys.Res.Commun., 2020
|
|
6KVP
| S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2) | Descriptor: | 3-[(1R)-1-[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]ethoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ... | Authors: | Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S. | Deposit date: | 2019-09-05 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Sci Rep, 9, 2019
|
|
3E22
| Tubulin-colchicine-soblidotin: Stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Cormier, A, Marchand, M, Ravelli, R.B, Knossow, M, Gigant, B. | Deposit date: | 2008-08-05 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural insight into the inhibition of tubulin by vinca domain peptide ligands Embo Rep., 9, 2008
|
|
3DU7
| Tubulin-colchicine-phomopsin A: Stathmin-like domain complex | Descriptor: | 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Cormier, A, Marchand, M, Ravelli, R.B, Knossow, M, Gigant, B. | Deposit date: | 2008-07-17 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural insight into the inhibition of tubulin by vinca domain peptide ligands Embo Rep., 9, 2008
|
|
8OU0
| |
3RYI
| GDP-Tubulin: rb3 stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nawrotek, A, Knossow, M, Gigant, B. | Deposit date: | 2011-05-11 | Release date: | 2011-10-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin. J.Mol.Biol., 412, 2011
|
|
3RYC
| Tubulin: RB3 stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nawrotek, A, Knossow, M, Gigant, B. | Deposit date: | 2011-05-11 | Release date: | 2011-10-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin. J.Mol.Biol., 412, 2011
|
|
3RYF
| GTP-Tubulin: RB3 Stathmin-like domain complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Nawrotek, A, Knossow, M, Gigant, B. | Deposit date: | 2011-05-11 | Release date: | 2011-10-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin. J.Mol.Biol., 412, 2011
|
|