3E22

Tubulin-colchicine-soblidotin: Stathmin-like domain complex

Summary for 3E22

• Entry DOI: 10.2210/pdb3e22/pdb
• Related: 1SA0 1Z2B 3DU7
• Descriptor: Tubulin alpha-1C chain, Tubulin beta-2B chain, Stathmin-4, ... (8 entities in total)
• Functional Keywords: alpha-tubulin, beta-tubulin, colchicine, gtpase, microtubule, soblidotin, stathmin, tubulin, cell cycle
• Biological source: RATTUS NORVEGICUS (rat); More
• Cellular location: Cytoplasm, cytoskeleton (By similarity): Q3ZCJ7 Q6B856
• Total number of polymer chains: 5
• Total formula weight: 220311.31

Authors

Cormier, A.,Marchand, M.,Ravelli, R.B.,Knossow, M.,Gigant, B. (deposition date: 2008-08-05, release date: 2008-10-21, Last modification date: 2023-11-01)

• Primary citation: Cormier, A.,Marchand, M.,Ravelli, R.B.,Knossow, M.,Gigant, B.; Structural insight into the inhibition of tubulin by vinca domain peptide ligands; Embo Rep., 9:1101-1106, 2008; PubMed: 18787557; DOI: 10.1038/embor.2008.171

Experimental method

X-RAY DIFFRACTION (3.8 Å)