6EW0
Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol
Summary for 6EW0
Entry DOI | 10.2210/pdb6ew0/pdb |
EMDB information | 3961 3962 3963 3964 3965 |
Descriptor | Tubulin alpha-1B chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | microtubule, gtpase, tubulin, taxol, structural protein |
Biological source | Sus scrofa (Pig) More |
Total number of polymer chains | 12 |
Total formula weight | 611740.84 |
Authors | Manka, S.W. (deposition date: 2017-11-03, release date: 2018-07-04, Last modification date: 2019-12-11) |
Primary citation | Manka, S.W.,Moores, C.A. The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability. Nat. Struct. Mol. Biol., 25:607-615, 2018 Cited by PubMed: 29967541DOI: 10.1038/s41594-018-0087-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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