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6EW0

Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1E, J, C, L, A...Tubulin alpha-1B chainpolymer45150204.46UniProt (Q2XVP4)
Pfam (PF00091)
Pfam (PF03953)
In PDB
Sus scrofa (Pig)Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2F, G, D, I, B...Tubulin beta chainpolymer44549907.86UniProt (P02554)
Pfam (PF00091)
Pfam (PF03953)
In PDB
Sus scrofa (Pig)Beta-tubulin
3E, J, C, L, A...GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.26Chemie (GTP)
4E, J, C, L, A...MAGNESIUM IONnon-polymer24.36Chemie (MG)
5G, D, I, B, H...GUANOSINE-5'-DIPHOSPHATEnon-polymer443.26Chemie (GDP)
6G, D, I, B, H...TAXOLnon-polymer853.96Chemie (TA1)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight600673.3
Non-Polymers*Number of molecules24
Total formula weight11067.6
All*Total formula weight611740.8
*Water molecules are not included.

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PDB entries from 2024-09-04

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