8RIV

T2R-TTL-1-K08 complex

This is a non-PDB format compatible entry.

Summary for 8RIV

• Entry DOI: 10.2210/pdb8riv/pdb
• Descriptor: Tubulin alpha-1B chain, (4-fluoranyl-2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate, IMIDAZOLE, ... (13 entities in total)
• Functional Keywords: cell cycle, tubulin fold, cytoskeleton, microtubule
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 265435.26

Authors

Boiarska, Z.,Homer, J.A.,Steinmetz, M.O.,Moses, J.E.,Prota, A.E.P. (deposition date: 2023-12-19, release date: 2024-03-27)

• Primary citation: Homer, J.A.,Koelln, R.A.,Barrow, A.S.,Gialelis, T.L.,Boiarska, Z.,Steinohrt, N.S.,Lee, E.F.,Yang, W.H.,Johnson, R.M.,Chung, T.,Habowski, A.N.,Vishwakarma, D.S.,Bhunia, D.,Avanzi, C.,Moorhouse, A.D.,Jackson, M.,Tuveson, D.A.,Lyons, S.K.,Lukey, M.J.,Fairlie, W.D.,Haider, S.M.,Steinmetz, M.O.,Prota, A.E.,Moses, J.E.; Modular synthesis of functional libraries by accelerated SuFEx click chemistry.; Chem Sci, 15:3879-3892, 2024; PubMed: 38487227; DOI: 10.1039/d3sc05729a

Experimental method

X-RAY DIFFRACTION (2.78 Å)