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4NFB
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BU of 4nfb by Molmil
Structure of paired immunoglobulin-like type 2 receptor (PILR )
Descriptor: Paired immunoglobulin-like type 2 receptor alpha
Authors:Lu, Q, Lu, G, Qi, J, Li, Y, Zhang, Y, Wang, H, Fan, Z, Yan, J, Gao, G.
Deposit date:2013-10-31
Release date:2014-05-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid
Proc.Natl.Acad.Sci.USA, 111, 2014
2FBJ
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BU of 2fbj by Molmil
REFINED CRYSTAL STRUCTURE OF THE GALACTAN-BINDING IMMUNOGLOBULIN FAB J539 AT 1.95-ANGSTROMS RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IGA-KAPPA J539 FAB (HEAVY CHAIN), ...
Authors:Bhat, T.N, Padlan, E.A, Davies, D.R.
Deposit date:1989-08-18
Release date:1990-07-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Refined Crystal Structure of the Galactan-Binding Immunoglobulin Fab J539 at 1.95-Angstroms Resolution
To be Published
2FBO
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BU of 2fbo by Molmil
Crystal Structure of the Two Tandem V-type Regions of VCBP3 (v-region-containing chitin binding protein) to 1.85 A
Descriptor: variable region-containing chitin-binding protein 3
Authors:Hernandez Prada, J.A, Haire, R.N, Jakoncic, J, Cannon, J.P, Litman, G.W, Ostrov, D.A.
Deposit date:2005-12-09
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus
Nat.Immunol., 7, 2006
6C74
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BU of 6c74 by Molmil
Crystal Structure of Murine CD300lf in complex with phosphocholine
Descriptor: CALCIUM ION, CMRF35-like molecule-1, PHOSPHOCHOLINE
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-01-19
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.358 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2G5R
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BU of 2g5r by Molmil
Crystal structure of Siglec-7 in complex with methyl-9-(aminooxalyl-amino)-9-deoxyNeu5Ac (oxamido-Neu5Ac)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Sialic acid-binding Ig-like lectin 7, ...
Authors:Attrill, H, Crocker, P.R, van Aalten, D.M.
Deposit date:2006-02-23
Release date:2006-06-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design.
Biochem.J., 397, 2006
4ODX
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BU of 4odx by Molmil
4E10 germline encoded precursor no.7 in complex with epitope scaffold T117
Descriptor: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain
Authors:Finton, K.A.K.
Deposit date:2014-01-10
Release date:2014-10-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
4OFI
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BU of 4ofi by Molmil
Crystal Structure of Duf (Kirre) D1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kin of irre, isoform A, ...
Authors:Ozkan, E, Garcia, K.C.
Deposit date:2014-01-14
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
2GK2
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BU of 2gk2 by Molmil
Crystal structure of the N terminal domain of human CEACAM1
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, NICKEL (II) ION
Authors:Fedarovich, A, Tomberg, J, Nicholas, R.A, Davies, C.
Deposit date:2006-03-31
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae.
Acta Crystallogr.,Sect.D, 62, 2006
2HP4
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BU of 2hp4 by Molmil
Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor
Descriptor: GLYCEROL, SULFATE ION, T-cell surface glycoprotein CD8 alpha chain
Authors:Rizkallah, P.J, Cole, D.K, Jakobsen, B.K, Boulter, J.M, Glick, M, Gao, G.F.
Deposit date:2006-07-17
Release date:2007-02-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
2HRL
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BU of 2hrl by Molmil
Siglec-7 in complex with GT1b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ...
Authors:Attrill, H, Imamura, A, Sharma, R.S, Kiso, M, Crocker, P.R, van Aalten, D.M.F.
Deposit date:2006-07-20
Release date:2006-08-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Siglec-7 Undergoes a Major Conformational Change When Complexed with the {alpha}(2,8)-Disialylganglioside GT1b
J.Biol.Chem., 281, 2006
2DF3
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BU of 2df3 by Molmil
The structure of Siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl 2-(trimethylsilyl)ethyl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Attrill, H.
Deposit date:2006-02-23
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
Biochem.J., 397, 2006
2DLF
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BU of 2dlf by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FV FRAGMENT FROM AN ANTI-DANSYL SWITCH VARIANT ANTIBODY IGG2A(S) CRYSTALLIZED AT PH 6.75
Descriptor: PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S) (HEAVY CHAIN)), PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S)-KAPPA (LIGHT CHAIN)), SULFATE ION
Authors:Nakasako, M, Takahashi, H, Shimada, I, Arata, Y.
Deposit date:1998-12-17
Release date:1999-12-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody.
J.Mol.Biol., 291, 1999
2DDQ
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BU of 2ddq by Molmil
Crystal Structure of the Fab fragment of a R310 antibody complexed with (R)-HNE-histidine adduct
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-ACETYL-1-[(2R,3S,5R)-5-HYDROXY-2-PENTYLTETRAHYDROFURAN-3-YL]-L-HISTIDINE, R310 antibody heavy chain, ...
Authors:Ito, S.
Deposit date:2006-02-02
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Bispecific abs against modified protein and DNA with oxidized lipids
Proc.Natl.Acad.Sci.Usa, 103, 2006
2DKS
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BU of 2dks by Molmil
Solution structure of the first IG-like domain of human carcinoembryonic antigen related cell adhesion molecule 8
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 8
Authors:Nagashima, K, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-14
Release date:2007-05-01
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the first IG-like domain of human carcinoembryonic antigen related cell adhesion molecule 8
To be Published
2I27
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BU of 2i27 by Molmil
Crystal Structure Analysis of the Nurse Shark New Antigen Receptor Ancestral variable domain
Descriptor: New Antigen Receptor Ancestral
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
2D7T
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BU of 2d7t by Molmil
Crystal structure of human anti polyhydroxybutyrate antibody Fv
Descriptor: anti polyhydroxybutyrate antibody Fv, heavy chain, light chain
Authors:Watanabe, H.
Deposit date:2005-11-29
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A human antibody fragment with high affinity for the biodegradable polymer film
To be Published
2D9C
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BU of 2d9c by Molmil
Solution structure of the first ig-like domain of signal-regulatory protein beta-1 (SIRP-beta-1)
Descriptor: Signal-regulatory protein beta-1
Authors:Nagashima, K, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-09
Release date:2006-12-09
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the first ig-like domain of signal-regulatory protein beta-1 ( SIRP-beta-1)
To be Published
2I24
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BU of 2i24 by Molmil
Crystal structure analysis of the nurse shark New Antigen Receptor PBLA8 variable domain
Descriptor: CHLORIDE ION, New Antigen Receptor PBLA8
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
1MAJ
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BU of 1maj by Molmil
SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN
Descriptor: IGG2A-KAPPA 26-10 FV (LIGHT CHAIN)
Authors:Constantine, K.L, Friedrichs, M.S, Metzler, W.J, Wittekind, M, Hensley, P, Mueller, L.
Deposit date:1993-09-16
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of an isolated antibody VL domain.
J.Mol.Biol., 236, 1994
1MCW
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BU of 1mcw by Molmil
THREE-DIMENSIONAL STRUCTURE OF A HYBRID LIGHT CHAIN DIMER. PROTEIN ENGINEERING OF A BINDING CAVITY
Descriptor: IMMUNOGLOBULIN MCG (LIGHT CHAIN), IMMUNOGLOBULIN WEIR (LIGHT CHAIN)
Authors:Ely, K.R, Herron, J.N, Edmundson, A.B.
Deposit date:1989-05-09
Release date:1990-10-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Three-dimensional structure of a hybrid light chain dimer: protein engineering of a binding cavity.
Mol.Immunol., 27, 1990
1MOE
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BU of 1moe by Molmil
The three-dimensional structure of an engineered scFv T84.66 dimer or diabody in VL to VH linkage.
Descriptor: SULFATE ION, anti-CEA mAb T84.66
Authors:Carmichael, J.A, Power, B.E, Garrett, T.P.J, Yazaki, P.J, Shively, J.E, Raubischek, A.A, Wu, A.M, Hudson, P.J.
Deposit date:2002-09-09
Release date:2003-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of an Anti-CEA scFv Diabody Assembled from T84.66 scFvs in VL-to-VH Orientation: Implications for Diabody Flexibility
J.Mol.Biol., 326, 2003
1MAK
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BU of 1mak by Molmil
SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN
Descriptor: IGG2A-KAPPA 26-10 FV (LIGHT CHAIN)
Authors:Constantine, K.L, Friedrichs, M.S, Metzler, W.J, Wittekind, M, Hensley, P, Mueller, L.
Deposit date:1993-09-16
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of an isolated antibody VL domain.
J.Mol.Biol., 236, 1994
1MVU
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BU of 1mvu by Molmil
SINGLE CHAIN FV OF C219 HEAVY CHAIN V101L MUTANT IN COMPLEX WITH SYNTHETIC EPITOPE PEPTIDE
Descriptor: Ig VDJ-region (HEAVY CHAIN), Ig kappa-chain VJ-region (Light chain), P-GLYCOPROTEIN, ...
Authors:Chan, D.C.M, Kuntz, D.A, Rose, D.R.
Deposit date:2002-09-26
Release date:2003-10-07
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Single Chain C219 V(101H)L Mutant Antibody Complexed with a Helical Peptide
To be Published
1N4X
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BU of 1n4x by Molmil
Structure of scFv 1696 at acidic pH
Descriptor: CHLORIDE ION, immunoglobulin heavy chain variable region, immunoglobulin kappa chain variable region
Authors:Lescar, J, Brynda, J, Fabry, M, Horejsi, M, Rezacova, P, Sedlacek, J, Bentley, G.A.
Deposit date:2002-11-02
Release date:2003-06-10
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a single-chain Fv fragment of an antibody that inhibits the HIV-1 and HIV-2 proteases.
Acta Crystallogr.,Sect.D, 59, 2003
1NGW
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BU of 1ngw by Molmil
Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin
Descriptor: Mature Metal Chelatase Catalytic Antibody, Heavy chain, Light chain, ...
Authors:Yin, J, Andryski, S.E, Beuscher IV, A.E, Stevens, R.C, Schultz, P.G.
Deposit date:2002-12-18
Release date:2003-02-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003

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