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6CXY
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Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody Fab mAb-1_19A11
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Cadherin-1, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-04-04
Release date:2019-04-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody Fab mAb-1_19A11
to be published
7WP5
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BU of 7wp5 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spikeprotein S1, VacW-209 heavy chain, ...
Authors:Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N.
Deposit date:2022-01-22
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.
Cell Res., 32, 2022
7WP2
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Cryo-EM structure of SARS-CoV-2 C.1.2 S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ...
Authors:Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N.
Deposit date:2022-01-22
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.
Cell Res., 32, 2022
7WP0
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BU of 7wp0 by Molmil
Cryo-EM structure of SARS-CoV-2 Delta S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c335_light_IGLV1-40_IGLJ3, Spike protein S1, ...
Authors:Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N.
Deposit date:2022-01-22
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.
Cell Res., 32, 2022
7LG6
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BU of 7lg6 by Molmil
BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Cottrell, C.A, Torres, J.L, Wu, N.R, Ward, A.B.
Deposit date:2021-01-19
Release date:2021-09-15
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.
Cell Rep, 37, 2021
7XLI
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BU of 7xli by Molmil
Crystal structure of IsdB linker-NEAT2 bound to a nanobody (VHH)
Descriptor: CALCIUM ION, CHLORIDE ION, Iron-regulated surface determinant protein B, ...
Authors:Caaveiro, J.M.M, Valenciano-Bellido, S, Tsumoto, K.
Deposit date:2022-04-21
Release date:2023-05-31
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth.
J.Biol.Chem., 299, 2023
6BE2
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BU of 6be2 by Molmil
Crystal structure of a polysaccharide-binding human Fab (F598)
Descriptor: Fab (F598) Heavy Chain, Fab (F598) Light Chain
Authors:Soliman, C, Ramsland, P.A.
Deposit date:2017-10-24
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine.
J. Biol. Chem., 293, 2018
6VJN
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BU of 6vjn by Molmil
Structure of NHP D11A.B5Fab in complex with 16055 V2b peptide
Descriptor: D11A.B5 Fab Heavy chain, D11A.B5 Fab Light chain, SODIUM ION, ...
Authors:Singh, S, Liban, T.J, Pancera, M.
Deposit date:2020-01-16
Release date:2021-01-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
3OP8
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BU of 3op8 by Molmil
Crystal structure of the domain V from beta2-glycoprotein I
Descriptor: Beta-2-glycoprotein 1, SULFATE ION
Authors:Kolyada, A, Lee, C.-J, De Biasio, A, Beglova, N.
Deposit date:2010-08-31
Release date:2011-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Novel Dimeric Inhibitor Targeting Beta2GPI in Beta2GPI/Antibody Complexes Implicated in Antiphospholipid Syndrome.
Plos One, 5, 2010
7EW5
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BU of 7ew5 by Molmil
immune complex of HPV6 L1 pentamer and neutralizing antibody 13H5
Descriptor: Heavy chain of 13H5, Light chain of 13H5, Major capsid protein L1
Authors:Wang, Z.P, Wang, D.N, Gu, Y, Li, S.W.
Deposit date:2021-05-24
Release date:2022-06-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.606 Å)
Cite:structure of HPV6 L1 pentamer in complex with neutralizing antibody 13H5
To Be Published
8DCE
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BU of 8dce by Molmil
SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 1 Bound to C144 scFv
Descriptor: C144 scFv, Spike protein S1
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-06-16
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.
Sci Adv, 8, 2022
6NNJ
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BU of 6nnj by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to CH31 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.1 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2019-01-15
Release date:2019-02-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Improvement of antibody functionality by structure-guided paratope engraftment.
Nat Commun, 10, 2019
6NNF
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BU of 6nnf by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to VRC01 FR3-03 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2019-01-14
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.762 Å)
Cite:Improvement of antibody functionality by structure-guided paratope engraftment.
Nat Commun, 10, 2019
6O26
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BU of 6o26 by Molmil
Crystal structure of 3246 Fab in complex with circumsporozoite protein NANA
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3246 Fab heavy chain, ...
Authors:Scally, S.W, Bosch, A, Castro, K, Murugan, R, Wardemann, H, Julien, J.P.
Deposit date:2019-02-22
Release date:2020-03-04
Last modified:2020-09-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
6NM6
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BU of 6nm6 by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to N6 FR3-03 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.2 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2019-01-10
Release date:2019-02-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.739 Å)
Cite:Improvement of antibody functionality by structure-guided paratope engraftment.
Nat Commun, 10, 2019
6O2C
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BU of 6o2c by Molmil
Crystal structure of 4493 Fab in complex with circumsporozoite protein NANP3 and anti-kappa VHH domain
Descriptor: 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ...
Authors:Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P.
Deposit date:2019-02-22
Release date:2020-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.017 Å)
Cite:Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
6O24
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BU of 6o24 by Molmil
Crystal structure of 4498 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain
Descriptor: 1,2-ETHANEDIOL, 4498 Fab heavy chain, 4498 Kappa light chain, ...
Authors:Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P.
Deposit date:2019-02-22
Release date:2020-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
7TXW
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BU of 7txw by Molmil
Crystal structure of the complex of the malaria sexual stage protein and vaccine target Pfs25 with the Fab fragment of a transmission blocking antibody 1G2
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ETHANOL, ...
Authors:Singh, K, Gittis, A.G, Garboczi, D.N.
Deposit date:2022-02-10
Release date:2023-04-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles.
Npj Vaccines, 8, 2023
8GNH
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BU of 8gnh by Molmil
Complex structure of BD-218 and Spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BD-218, ...
Authors:Wang, B, Xu, H, Su, X.D.
Deposit date:2022-08-23
Release date:2023-08-30
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Human antibody BD-218 has broad neutralizing activity against concerning variants of SARS-CoV-2.
Int.J.Biol.Macromol., 227, 2023
6O28
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BU of 6o28 by Molmil
Crystal structure of 4493 Fab in complex with circumsporozoite protein KQPA and anti-kappa VHH domain
Descriptor: 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ...
Authors:Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P.
Deposit date:2019-02-22
Release date:2020-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
6O23
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BU of 6o23 by Molmil
Crystal structure of 2243 Fab in complex with circumsporozoite protein NANP5
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2243 Fab heavy chain, ...
Authors:Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P.
Deposit date:2019-02-22
Release date:2020-03-04
Last modified:2020-09-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
6XMI
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BU of 6xmi by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
Descriptor: Fab Heavy chain, Fab Light chain, Terminase, ...
Authors:Cingolani, G, Lokareddy, R, Ko, Y.
Deposit date:2020-06-30
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6O2B
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BU of 6o2b by Molmil
Crystal structure of 4493 Fab in complex with circumsporozoite protein DND and anti-kappa VHH domain
Descriptor: 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ...
Authors:Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P.
Deposit date:2019-02-22
Release date:2020-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
8DEC
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BU of 8dec by Molmil
Cryo-EM Structure of Western Equine Encephalitis Virus
Descriptor: Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2
Authors:Pletnev, S, Verardi, R, Roedeger, M, Kwong, P.
Deposit date:2022-06-20
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DEE
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BU of 8dee by Molmil
Asymmetric Unit of Western Equine Encephalitis Virus
Descriptor: Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2
Authors:Pletnev, S, Verardi, R, Roedeger, M, Kwong, P.
Deposit date:2022-06-20
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023

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