8DCE

SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 1 Bound to C144 scFv

Summary for 8DCE

Entry DOI	10.2210/pdb8dce/pdb
Descriptor	C144 scFv, Spike protein S1 (3 entities in total)
Functional Keywords	immunogen, antigen, design, vaccine, viral protein-immune system complex, viral protein/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	52568.63
Authors	Tang, W.K.,Tolia, N.H. (deposition date: 2022-06-16, release date: 2022-06-29, Last modification date: 2023-10-18)
Primary citation	Dickey, T.H.,Tang, W.K.,Butler, B.,Ouahes, T.,Orr-Gonzalez, S.,Salinas, N.D.,Lambert, L.E.,Tolia, N.H. Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response. Sci Adv, 8:eabq8276-eabq8276, 2022 Cited by PubMed: 36103542 DOI: 10.1126/sciadv.abq8276 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation