7LG6

BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs

Summary for 7LG6

• Entry DOI: 10.2210/pdb7lg6/pdb
• EMDB information: 23312
• Descriptor: Envelope glycoprotein gp120, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: antibody, hiv, sosip, env, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 18
• Total formula weight: 526219.81

Authors

Cottrell, C.A.,Torres, J.L.,Wu, N.R.,Ward, A.B. (deposition date: 2021-01-19, release date: 2021-09-15, Last modification date: 2021-11-17)

• Primary citation: Cottrell, C.A.,Manne, K.,Kong, R.,Wang, S.,Zhou, T.,Chuang, G.Y.,Edwards, R.J.,Henderson, R.,Janowska, K.,Kopp, M.,Lin, B.C.,Louder, M.K.,Olia, A.S.,Rawi, R.,Shen, C.H.,Taft, J.D.,Torres, J.L.,Wu, N.R.,Zhang, B.,Doria-Rose, N.A.,Cohen, M.S.,Haynes, B.F.,Shapiro, L.,Ward, A.B.,Acharya, P.,Mascola, J.R.,Kwong, P.D.; Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.; Cell Rep, 37:109922-109922, 2021; PubMed: 34731616; DOI: 10.1016/j.celrep.2021.109922

Experimental method

ELECTRON MICROSCOPY (3.28 Å)