PDB: 41877 resultsInfo pagesStatus searchChemie searchBIRD

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5AJK	Crystal structure of variola virus virulence factor F1L in complex with human Bak BH3 domain Descriptor: ACETATE ION, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, CHLORIDE ION, ... Authors: Kvansakul, M, Colman, P.M. Deposit date: 2015-02-25 Release date: 2015-03-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim. Cell Death Dis., 6, 2015
3BMB	Crystal structure of a new RNA polymerase interacting protein Descriptor: CHLORIDE ION, Regulator of nucleoside diphosphate kinase, SULFATE ION Authors: Darst, S.A, Lamour, V. Deposit date: 2007-12-12 Release date: 2008-10-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Crystal structure of Escherichia coli Rnk, a new RNA polymerase-interacting protein. J.Mol.Biol., 383, 2008
3BN4	Carboxysome Subunit, CcmK1 Descriptor: Carbon dioxide-concentrating mechanism protein ccmK homolog 1, SULFATE ION Authors: Tanaka, S, Sawaya, M.R, Yeates, T.O. Deposit date: 2007-12-13 Release date: 2008-03-04 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Atomic-level models of the bacterial carboxysome shell. Science, 319, 2008
3VVV	Skich domain of NDP52 Descriptor: Calcium-binding and coiled-coil domain-containing protein 2 Authors: Akutsu, M, Muhlinen, N.V, Randow, F, Komander, D. Deposit date: 2012-07-28 Release date: 2013-02-27 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.35 Å) Cite: LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy Mol.Cell, 48, 2012
5THL	Crystal structure of the human tyrosyl-tRNA synthetase mutant G41R Descriptor: Tyrosine--tRNA ligase, cytoplasmic Authors: Blocquel, D, Sajish, M, Yang, X.L. Deposit date: 2016-09-29 Release date: 2017-06-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy. Nucleic Acids Res., 45, 2017
1W4H	Peripheral-subunit from mesophilic, thermophilic and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions Descriptor: DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE Authors: Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Fersht, A.R. Deposit date: 2004-07-23 Release date: 2005-07-20 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family. J.Mol.Biol., 353, 2005
5DXN	Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2 Descriptor: MAGNESIUM ION, trehalose-6-phosphate phosphatase Authors: Miao, Y, Brennan, R.G. Deposit date: 2015-09-23 Release date: 2016-06-15 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
5THH	Crystal structure of a human tyrosyl-tRNA synthetase mutant Descriptor: TYROSINE, Tyrosine--tRNA ligase, cytoplasmic Authors: Blocquel, D, Yang, X.L. Deposit date: 2016-09-29 Release date: 2017-05-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.959 Å) Cite: Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy. Nucleic Acids Res., 45, 2017
4OKV	Crystal structure of anopheline anti-platelet protein with Fab antibody Descriptor: Anti-platelet aggregation protein, heavy chain of 8H7 mAb, light chain of 8H7 mAb Authors: Park, S.Y, Sugiyama, K. Deposit date: 2014-01-23 Release date: 2014-04-30 Method: X-RAY DIFFRACTION (1.802 Å) Cite: The crystal structure of anopheles anti-platelet protein, a powerful anti-coagulant, in complex with an antibody To be Published
2X0U	STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-amino substituted benzothiazole scaffold Descriptor: 6,7-DIHYDRO[1,4]DIOXINO[2,3-F][1,3]BENZOTHIAZOL-2-AMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION Authors: Joerger, A.C, Kaar, J.L, Basse, N, Fersht, A.R. Deposit date: 2009-12-17 Release date: 2010-01-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol., 17, 2010
5BRV	Catalytic Improvement of an Artificial Metalloenzyme by Computational Design Descriptor: Carbonic anhydrase 2, ZINC ION, pentamethylcyclopentadienyl iridium [N-benzensulfonamide-(2-pyridylmethyl-4-benzensulfonamide)amin] chloride Authors: Heinisch, T, Pellizzoni, M, Duerrenberger, M, Tinberg, C.E, Koehler, V, Klehr, J, Haeussinger, D, Baker, D, Ward, T.R. Deposit date: 2015-06-01 Release date: 2015-06-24 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design. J.Am.Chem.Soc., 137, 2015
5VD6	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 6 Descriptor: (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name), SULFATE ION, acetyltransferase PA4794 Authors: Majorek, K.A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) Deposit date: 2017-04-01 Release date: 2017-07-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases. FEBS Lett., 591, 2017
5DX9	Structure of trehalose-6-phosphate phosphatase from Cryptococcus neoformans Descriptor: 6-O-phosphono-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... Authors: Miao, Y, Brennan, R.G. Deposit date: 2015-09-23 Release date: 2016-06-15 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
5DXO	Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 3 Descriptor: MAGNESIUM ION, trehalose-6-phosphate phosphatase Authors: Miao, Y, Brennan, R.G. Deposit date: 2015-09-23 Release date: 2016-06-15 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
1GA1	CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH A FRAGMENT OF IODOTYROSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) Descriptor: CALCIUM ION, CHLORIDE ION, FRAGMENT OF IODOTYROSTATIN, ... Authors: Dauter, Z, Li, M, Wlodawer, A. Deposit date: 2000-11-29 Release date: 2000-12-13 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Practical experience with the use of halides for phasing macromolecular structures: a powerful tool for structural genomics. Acta Crystallogr.,Sect.D, 57, 2001
4GNK	Crystal structure of Galphaq in complex with full-length human PLCbeta3 Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Lyon, A.M, Tesmer, J.J.G. Deposit date: 2012-08-17 Release date: 2013-02-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (4 Å) Cite: Full-length G alpha (q)-phospholipase C-beta 3 structure reveals interfaces of the C-terminal coiled-coil domain. Nat.Struct.Mol.Biol., 20, 2013
3U0X	Crystal structure of the B-specific-1,3-galactosyltransferase (GTB) in complex with compound 382 Descriptor: 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine, CHLORIDE ION, GLYCEROL, ... Authors: Palcic, M.M, Jorgensen, R. Deposit date: 2011-09-29 Release date: 2012-10-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A novel compound from a molecular fragment library screen inhibits glycosyltransferases by displacing the metal ion and interfering with substrate binding To be Published
5BRU	Catalytic Improvement of an Artificial Metalloenzyme by Computational Design Descriptor: Carbonic anhydrase 2, SULFATE ION, ZINC ION, ... Authors: Heinisch, T, Pellizzoni, M, Duerrenberger, M, Tinberg, C.E, Koehler, V, Klehr, J, Haeussinger, D, Baker, D, Ward, T.R. Deposit date: 2015-06-01 Release date: 2015-06-24 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design. J.Am.Chem.Soc., 137, 2015
2GR3	Crystal structure of Ferredoxin reductase, BphA4 (oxidized form) Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLYCEROL, ... Authors: Senda, T, Senda, M. Deposit date: 2006-04-22 Release date: 2007-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A ferredoxin reductase BphA4 uses a butterfly motion of FAD to regulate affinity for ferredoxin To be Published
2GR1	Crystal structure of Ferredoxin reductase, BphA4 (hydroquinone) Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, ferredoxin reductase Authors: Senda, T, Senda, M. Deposit date: 2006-04-22 Release date: 2007-05-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A ferredoxin reductase BphA4 uses a butterfly motion of FAD to regulate affinity for ferredoxin To be Published
2GR2	Crystal structure of Ferredoxin reductase, BphA4 (oxidized form) Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, FLAVIN-ADENINE DINUCLEOTIDE, ferredoxin reductase Authors: Senda, T, Senda, M. Deposit date: 2006-04-22 Release date: 2007-05-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A ferredoxin reductase BphA4 uses a butterfly motion of FAD to regulate affinity for ferredoxin To be Published
1XF4	Structure of ligand-free Fab DNA-1 in space group P321 solved from crystals with perfect hemihedral twinning Descriptor: Fab heavy chain, Fab light chain, SULFATE ION Authors: Schuermann, J.P, Prewitt, S.P, Deutscher, S.L, Tanner, J.J. Deposit date: 2004-09-13 Release date: 2005-04-12 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Evidence for Structural Plasticity of Heavy Chain Complementarity-determining Region 3 in Antibody-ssDNA Recognition J.Mol.Biol., 347, 2005
5VYY	Structure of human Hsp90-alpha bound to resorcinylic inhibitor BnIm Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Heat shock protein HSP 90-alpha, ... Authors: Que, N.S, Gewirth, D.T. Deposit date: 2017-05-26 Release date: 2018-04-18 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.792 Å) Cite: Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. J. Med. Chem., 61, 2018
3U0Y	Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with compound 382 and UDP Descriptor: 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine, GLYCEROL, Histo-blood group ABO system transferase, ... Authors: Palcic, M.M, Jorgensen, R. Deposit date: 2011-09-29 Release date: 2012-10-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A novel compound from a molecular fragment library screen inhibits glycosyltransferases by displacing the metal ion and interfering with substrate binding To be Published
5DXI	Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ... Authors: Miao, Y, Brennan, R.G. Deposit date: 2015-09-23 Release date: 2016-06-15 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016

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