7MRZ
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![BU of 7mrz by Molmil](/molmil-images/mine/7mrz) | Structure of GDF11 bound to fused ActRIIB-ECD and Alk4-ECD with Anti-ActRIIB Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B,Activin receptor type-1B, Fab Heavy Chain, ... | Authors: | Goebel, E.J, Kattamuri, C, Gipson, G.R, Thompson, T.B. | Deposit date: | 2021-05-10 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors. Iscience, 25, 2022
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3DIS
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7MEP
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![BU of 7mep by Molmil](/molmil-images/mine/7mep) | |
7MDU
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![BU of 7mdu by Molmil](/molmil-images/mine/7mdu) | |
7MBH
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![BU of 7mbh by Molmil](/molmil-images/mine/7mbh) | Structure of Human Enolase 2 in complex with phosphoserine | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Gamma-enolase, ... | Authors: | Leonard, P.G, Hicks, K.G, Rutter, J. | Deposit date: | 2021-03-31 | Release date: | 2022-11-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science, 379, 2023
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3DCB
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![BU of 3dcb by Molmil](/molmil-images/mine/3dcb) | Crystal structure of the Drosophila kinesin family member NOD in complex with AMPPNP | Descriptor: | Kinesin-like protein Nod, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Cochran, J.C, Mulko, N.K, Kull, F.J. | Deposit date: | 2008-06-03 | Release date: | 2009-02-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.), 136, 2009
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3DIG
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3DIX
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7DV6
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![BU of 7dv6 by Molmil](/molmil-images/mine/7dv6) | Discovery of Functionally Selective Transforming Growth Factor beta Type II Receptor (TGF-beta RII) Inhibitors as Anti-Fibrosis Agents | Descriptor: | 5-[(3S)-5,5-dimethyloxolan-3-yl]-6-methoxy-3-(2-methoxypyridin-4-yl)pyrazolo[1,5-a]pyrimidine, TGF-beta receptor type-2 | Authors: | Nishihata, J, Nomura, A, Miwa, S, Doi, S, Adachi, T. | Deposit date: | 2021-01-12 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Discovery of Selective Transforming Growth Factor beta Type II Receptor Inhibitors as Antifibrosis Agents. Acs Med.Chem.Lett., 12, 2021
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7E5V
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![BU of 7e5v by Molmil](/molmil-images/mine/7e5v) | Crystal structure of Phm7 in complex with inhibitor | Descriptor: | Diels-Alderase, GLYCEROL, SULFATE ION, ... | Authors: | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | Deposit date: | 2021-02-20 | Release date: | 2021-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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7E5U
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![BU of 7e5u by Molmil](/molmil-images/mine/7e5u) | Crystal structure of Phm7 | Descriptor: | CHLORIDE ION, Diels-Alderase, GLYCEROL, ... | Authors: | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | Deposit date: | 2021-02-20 | Release date: | 2021-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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7E5T
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![BU of 7e5t by Molmil](/molmil-images/mine/7e5t) | Crystal structure of Fsa2 | Descriptor: | Diels-Alderase fsa2, ETHANOL, PENTAETHYLENE GLYCOL, ... | Authors: | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | Deposit date: | 2021-02-20 | Release date: | 2021-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.16977525 Å) | Cite: | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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5IFH
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![BU of 5ifh by Molmil](/molmil-images/mine/5ifh) | Crystal structure of the BCR Fab fragment from subset #2 case P11475 | Descriptor: | Heavy chain of the Fab fragment from BCR derived from the P11475 CLL clone, Light chain of the Fab fragment from BCR derived from the P11475 CLL clone | Authors: | Minici, C, Degano, M. | Deposit date: | 2016-02-26 | Release date: | 2017-03-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia. Nat Commun, 8, 2017
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6OCX
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5I51
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6URI
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8Q4K
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![BU of 8q4k by Molmil](/molmil-images/mine/8q4k) | Crystal structure of Borrelia burgdorferi BB0158 | Descriptor: | S2 lipoprotein, SULFATE ION | Authors: | Brangulis, K, Tars, K. | Deposit date: | 2023-08-07 | Release date: | 2024-01-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural studies of chromosomally encoded outer surface lipoprotein BB0158 from Borrelia burgdorferi sensu stricto. Ticks Tick Borne Dis, 15, 2024
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5I5E
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6OVG
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3NQW
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![BU of 3nqw by Molmil](/molmil-images/mine/3nqw) | A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses | Descriptor: | CG11900, MANGANESE (II) ION, SULFATE ION | Authors: | Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J. | Deposit date: | 2010-06-30 | Release date: | 2010-09-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses Nat.Struct.Mol.Biol., 17, 2010
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6OD0
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8SCH
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![BU of 8sch by Molmil](/molmil-images/mine/8sch) | TCEI_III NMR Structure | Descriptor: | RNA (68-MER) | Authors: | Warden, M.S, Mueller, G.A, Hall, T.M.T. | Deposit date: | 2023-04-05 | Release date: | 2023-07-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos. Nucleic Acids Res., 51, 2023
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8SCF
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![BU of 8scf by Molmil](/molmil-images/mine/8scf) | TCEIII NMR Structure | Descriptor: | RNA (30-MER) | Authors: | Warden, M.S, Mueller, G.A, Hall, T.M.T. | Deposit date: | 2023-04-05 | Release date: | 2023-07-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos. Nucleic Acids Res., 51, 2023
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7SXM
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7E6E
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![BU of 7e6e by Molmil](/molmil-images/mine/7e6e) | Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in D-cycloserine-inhibition | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2021-02-22 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 289, 2022
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