5IFH

Crystal structure of the BCR Fab fragment from subset #2 case P11475

Summary for 5IFH

• Entry DOI: 10.2210/pdb5ifh/pdb
• Descriptor: Heavy chain of the Fab fragment from BCR derived from the P11475 CLL clone, Light chain of the Fab fragment from BCR derived from the P11475 CLL clone (3 entities in total)
• Functional Keywords: immunoglobulin fold, b cell receptor, chronic lymphocytic leukemia, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 46976.19

Authors

Minici, C.,Degano, M. (deposition date: 2016-02-26, release date: 2017-03-08, Last modification date: 2024-01-10)

• Primary citation: Minici, C.,Gounari, M.,Ubelhart, R.,Scarfo, L.,Duhren-von Minden, M.,Schneider, D.,Tasdogan, A.,Alkhatib, A.,Agathangelidis, A.,Ntoufa, S.,Chiorazzi, N.,Jumaa, H.,Stamatopoulos, K.,Ghia, P.,Degano, M.; Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia.; Nat Commun, 8:15746-15746, 2017; PubMed: 28598442; DOI: 10.1038/ncomms15746

Experimental method

X-RAY DIFFRACTION (2.293 Å)