7MBH

Structure of Human Enolase 2 in complex with phosphoserine

Summary for 7MBH

• Entry DOI: 10.2210/pdb7mbh/pdb
• Related: 4ZA0 4ZCW 5EU9 5IDZ 5TD9 5TIJ
• Descriptor: Gamma-enolase, PHOSPHATE ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 97022.61

Authors

Leonard, P.G.,Hicks, K.G.,Rutter, J. (deposition date: 2021-03-31, release date: 2022-11-09, Last modification date: 2023-10-25)

• Primary citation: Hicks, K.G.,Cluntun, A.A.,Schubert, H.L.,Hackett, S.R.,Berg, J.A.,Leonard, P.G.,Ajalla Aleixo, M.A.,Zhou, Y.,Bott, A.J.,Salvatore, S.R.,Chang, F.,Blevins, A.,Barta, P.,Tilley, S.,Leifer, A.,Guzman, A.,Arok, A.,Fogarty, S.,Winter, J.M.,Ahn, H.C.,Allen, K.N.,Block, S.,Cardoso, I.A.,Ding, J.,Dreveny, I.,Gasper, W.C.,Ho, Q.,Matsuura, A.,Palladino, M.J.,Prajapati, S.,Sun, P.,Tittmann, K.,Tolan, D.R.,Unterlass, J.,VanDemark, A.P.,Vander Heiden, M.G.,Webb, B.A.,Yun, C.H.,Zhao, P.,Wang, B.,Schopfer, F.J.,Hill, C.P.,Nonato, M.C.,Muller, F.L.,Cox, J.E.,Rutter, J.; Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase.; Science, 379:996-1003, 2023; PubMed: 36893255; DOI: 10.1126/science.abm3452

Experimental method

X-RAY DIFFRACTION (2.1 Å)