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5CJ7	Human DNA polymerase lambda L431A mutant- MgdTTP binary and complex with 6 paired DNA Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ... Authors: Liu, M.S, Tsai, M.D. Deposit date: 2015-07-14 Release date: 2016-02-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.901 Å) Cite: Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016
1ONB	Solution structure of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase Descriptor: helicase NS3 Authors: Liu, D, Wang, Y.S, Gesell, J.J, Wyss, D.F. Deposit date: 2003-02-27 Release date: 2003-03-11 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase J.Mol.Biol., 314, 2001
3PZP	Human DNA polymerase kappa extending opposite a cis-syn thymine dimer Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*A)-3', 5'-D(*TP*TP*CP*CP*(TTD)P*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... Authors: Vasquez-Del Carpio, R, Silverstein, T.D, Lone, S, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K. Deposit date: 2010-12-14 Release date: 2011-12-28 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.336 Å) Cite: Role of human DNA polymerase kappa in extension opposite from a cis-syn thymine dimer. J.Mol.Biol., 408, 2011
2RDJ	Snapshots of a Y-family DNA polymerase in replication: Dpo4 in apo and binary/ternary complex forms Descriptor: CALCIUM ION, DNA (5'-D(*DGP*DGP*DGP*DAP*DCP*DCP*DCP*DTP*DTP*DCP*DGP*DAP*DAP*DT)-3'), DNA (5'-D(P*DTP*DAP*DTP*DTP*DCP*DGP*DAP*DAP*DGP*DGP*DGP*DTP*DCP*DCP*DC)-3'), ... Authors: Wong, J.H.Y, Ling, H. Deposit date: 2007-09-24 Release date: 2008-06-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. J.Mol.Biol., 379, 2008
1TXS	STEM-LOOP D OF THE CLOVERLEAF DOMAIN OF ENTEROVIRAL 5'UTR RNA Descriptor: Enteroviral 5'-UTR Authors: Du, Z, Yu, J, Ulyanov, N.B, Andino, R, James, T.L. Deposit date: 2004-07-06 Release date: 2004-10-05 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution Structure of a Consensus Stem-Loop D RNA Domain that Plays Important Roles in Regulating Translation and Replication in Enteroviruses and Rhinoviruses Biochemistry, 43, 2004
3RH4	DNA Polymerase Beta with a dideoxy-terminated primer with an incoming ribonucleotide (rCTP) Descriptor: 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... Authors: Cavanaugh, N.A, Beard, W.A, Batra, V.K, Perera, L, Pedersen, L.G, Wilson, S.H. Deposit date: 2011-04-11 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.918 Å) Cite: Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. J.Biol.Chem., 286, 2011
2RDI	Snapshots of a Y-family DNA polymerase in replication: Dpo4 in apo and binary/ternary complex forms Descriptor: DI(HYDROXYETHYL)ETHER, DNA polymerase IV, GLYCEROL Authors: Wong, J.H.Y, Ling, H. Deposit date: 2007-09-24 Release date: 2008-06-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. J.Mol.Biol., 379, 2008
3RH5	DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming deoxynucleotide (dCTP) Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3', ... Authors: Cavanaugh, N.A, Beard, W.A, Batra, V.K, Perera, L, Pedersen, L.G, Wilson, S.H. Deposit date: 2011-04-11 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.096 Å) Cite: Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. J.Biol.Chem., 286, 2011
3RH6	DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming ribonucleotide (rCTP) Descriptor: (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3'), (5'-D(P*GP*TP*CP*GP*G)-3'), 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ... Authors: Cavanaugh, N.A, Beard, W.A, Batra, V.K, Perera, L, Pedersen, L.G, Wilson, S.H. Deposit date: 2011-04-11 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.048 Å) Cite: Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. J.Biol.Chem., 286, 2011
4ECR	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 40 sec Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.892 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
1AJF	SOLUTION STRUCTURE OF THE P5B STEM LOOP FROM A GROUP I INTRON COMPLEXED WITH COBALT (III) HEXAMMINE, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: COBALT HEXAMMINE(III), RNA (5'-R(*GP*AP*CP*AP*GP*GP*GP*GP*AP*AP*AP*CP*UP*UP*UP*GP*UP*C)-3') Authors: Kieft, J.S, Tinoco Junior, I. Deposit date: 1997-05-02 Release date: 1997-07-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of a metal-binding site in the major groove of RNA complexed with cobalt (III) hexammine. Structure, 5, 1997
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... Authors: Ling, H. Deposit date: 2008-11-26 Release date: 2009-01-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009
3GEY	Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment in complex with an inhibitor Pj34 Descriptor: N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Poly [ADP-ribose] polymerase 15 Authors: Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) Deposit date: 2009-02-26 Release date: 2009-03-24 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015
2A0C	Human CDK2 in complex with olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor Descriptor: 2-{[(2-{[(1R)-1-(HYDROXYMETHYL)PROPYL]AMINO}-9-ISOPROPYL-9H-PURIN-6-YL)AMINO]METHYL}PHENOL, Cell division protein kinase 2 Authors: Krystof, V, McNae, I.W, Walkinshaw, M.D, Fischer, P.M, Muller, P, Vojtesek, B, Orsag, M, Havlicek, L, Strnad, M. Deposit date: 2005-06-16 Release date: 2006-01-24 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor Cell.Mol.Life Sci., 62, 2005
2PZS	Phi29 DNA polymerase complexed with primer-template DNA (post-translocation binary complex) Descriptor: 5'-d(CTAACACGTAAGCAGTC)-3', 5'-d(GACTGCTTAC)-3', DNA polymerase Authors: Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. Deposit date: 2007-05-18 Release date: 2007-07-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases Embo J., 26, 2007
2PY5	Phi29 DNA polymerase complexed with single-stranded DNA Descriptor: 1,2-ETHANEDIOL, 5'-d(GGACTTT)-3', DNA polymerase Authors: Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. Deposit date: 2007-05-15 Release date: 2007-07-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases Embo J., 26, 2007
4P4M	Crystal structure of Leishmania infantum polymerase beta: Ternary P/T complex Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*A)-3'), DNA (5'-D(P*AP*TP*AP*CP*TP*G)-3'), ... Authors: Mejia, E, Burak, M, Alonso, A, Larraga, V, Kunkel, T.A, Bebenek, K, Garcia-Diaz, M. Deposit date: 2014-03-12 Release date: 2014-08-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9185 Å) Cite: Structures of the Leishmania infantum polymerase beta. DNA Repair (Amst.), 18, 2014
2Z7J	Structural insights into de multifunctional VP3 protein of birnaviruses:gold derivative Descriptor: Capsid assembly protein VP3, GOLD ION Authors: Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N. Deposit date: 2007-08-23 Release date: 2008-02-05 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural insights into the multifunctional protein VP3 of birnaviruses. Structure, 16, 2008
3HPO	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus Y714S mutant bound to G:T mismatch Descriptor: 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DOC))-3', 5'-D(P*GP*GP*CP*GP*TP*GP*AP*TP*CP*G)-3', DNA polymerase I, ... Authors: Wu, E.Y, Beese, L.S. Deposit date: 2009-06-04 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. J.Biol.Chem., 286, 2011
4ED8	Human DNA polymerase eta - DNA ternary complex: Reaction in the TG crystal at pH 7.0, Normal translocation Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*G)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-27 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.521 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4P4O	Crystal structure of Leishmania infantum polymerase beta: Ternary gap complex Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*T)-3'), DNA (5'-D(P*CP*GP*GP*CP*AP*AP*TP*AP*CP*TP*G)-3'), ... Authors: Mejia, E, Burak, M, Alonso, A, Larraga, V, Kunkel, T, Bebenek, K, Garcia-Diaz, M. Deposit date: 2014-03-12 Release date: 2014-08-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.3001 Å) Cite: Structures of the Leishmania infantum polymerase beta. DNA Repair (Amst.), 18, 2014
1IK1	Solution Structure of an RNA Hairpin from HRV-14 Descriptor: 5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3' Authors: Huang, H, Alexandrov, A, Chen, X, Barnes III, T.W, Zhang, H, Dutta, K, Pascal, S.M. Deposit date: 2001-05-01 Release date: 2001-07-18 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structure of an RNA hairpin from HRV-14. Biochemistry, 40, 2001
3NAE	RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... Authors: Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. Deposit date: 2010-06-01 Release date: 2010-09-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.003 Å) Cite: Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
1OQ0	P6.1 stem loop from the activation domain of hTR Descriptor: P6.1 RNA hairpin from hTR Authors: Leeper, T, Leulliot, N, Varani, G. Deposit date: 2003-03-06 Release date: 2003-05-13 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The solution structure of an essential stem-loop of human telomerase RNA NUCLEIC ACIDS RES., 31, 2003
4BPX	Crystal structure of human primase in complex with the primase- binding motif of DNA polymerase alpha Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT, DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, ... Authors: Kilkenny, M.L, Perera, R.L, Pellegrini, L. Deposit date: 2013-05-28 Release date: 2013-09-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering Proc.Natl.Acad.Sci.USA, 110, 2013

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