3RH5

DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming deoxynucleotide (dCTP)

Summary for 3RH5

• Entry DOI: 10.2210/pdb3rh5/pdb
• Related: 3RH4 3RH6
• Descriptor: DNA polymerase beta, 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3', ... (9 entities in total)
• Functional Keywords: dna polymerase beta mutant, nucleotide transferase, ribonucleotide insertion, dctp, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P06746
• Total number of polymer chains: 4
• Total formula weight: 49141.90

Authors

Cavanaugh, N.A.,Beard, W.A.,Batra, V.K.,Perera, L.,Pedersen, L.G.,Wilson, S.H. (deposition date: 2011-04-11, release date: 2011-07-06, Last modification date: 2023-09-13)

• Primary citation: Cavanaugh, N.A.,Beard, W.A.,Batra, V.K.,Perera, L.,Pedersen, L.G.,Wilson, S.H.; Molecular insights into DNA polymerase deterrents for ribonucleotide insertion.; J.Biol.Chem., 286:31650-31660, 2011; PubMed: 21733843; DOI: 10.1074/jbc.M111.253401

Experimental method

X-RAY DIFFRACTION (2.096 Å)