3RH5
DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming deoxynucleotide (dCTP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA polymerase beta | polymer | 335 | 38149.6 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) In PDB | Homo sapiens (human) | |
| 2 | T | 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3' | polymer | 16 | 4829.1 | 1 | |||
| 3 | P | 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3' | polymer | 10 | 3085.0 | 1 | |||
| 4 | D | 5'-D(P*GP*TP*CP*GP*G)-3' | polymer | 5 | 1536.0 | 1 | |||
| 5 | A | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 2 | Chemie (DCP) | |||
| 6 | A, T, D | MANGANESE (II) ION | non-polymer | 54.9 | 7 | Chemie (MN) | |||
| 7 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 8 | A | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 9 | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A: 1 - 335 (UniProt: P06746)
| PDB | External Database | Details |
|---|---|---|
| Ala 271 | Tyr 271 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 47599.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1542.1 | |
| All* | Total formula weight | 49141.9 |
