3RH4

DNA Polymerase Beta with a dideoxy-terminated primer with an incoming ribonucleotide (rCTP)

Summary for 3RH4

Related3RH5 3RH6
Descriptor5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... (9 entities in total)
Functional Keywordsdna polymerase, ribonucleotide insertion, rctp, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight49356.38
Authors
Cavanaugh, N.A.,Beard, W.A.,Batra, V.K.,Perera, L.,Pedersen, L.G.,Wilson, S.H. (deposition date: 2011-04-11, release date: 2011-07-06, Last modification date: 2011-09-21)
Primary citation
Cavanaugh, N.A.,Beard, W.A.,Batra, V.K.,Perera, L.,Pedersen, L.G.,Wilson, S.H.
Molecular insights into DNA polymerase deterrents for ribonucleotide insertion.
J.Biol.Chem., 286:31650-31660, 2011
PubMed: 21733843 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M111.253401
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.918 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.233701.4%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution