3PZP

Human DNA polymerase kappa extending opposite a cis-syn thymine dimer

Summary for 3PZP

• Entry DOI: 10.2210/pdb3pzp/pdb
• Related: 1T94 2OH2 3IN5
• Descriptor: DNA polymerase kappa, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*A)-3', 5'-D(*TP*TP*CP*CP*(TTD)P*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
• Functional Keywords: dna nucleotidyltransferase, dna binding nucleotide binding magnesium binding, nucleus, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9UBT6
• Total number of polymer chains: 6
• Total formula weight: 137754.20

Authors

Vasquez-Del Carpio, R.,Silverstein, T.D.,Lone, S.,Johnson, R.E.,Prakash, S.,Prakash, L.,Aggarwal, A.K. (deposition date: 2010-12-14, release date: 2011-12-28, Last modification date: 2023-09-13)

• Primary citation: Vasquez-Del Carpio, R.,Silverstein, T.D.,Lone, S.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Role of human DNA polymerase kappa in extension opposite from a cis-syn thymine dimer.; J.Mol.Biol., 408:252-261, 2011; PubMed: 21354175; DOI: 10.1016/j.jmb.2011.02.042

Experimental method

X-RAY DIFFRACTION (3.336 Å)