3PZP

Human DNA polymerase kappa extending opposite a cis-syn thymine dimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA polymerase kappa	polymer	517	58901.2	2	UniProt (Q9UBT6) Pfam (PF00817) Pfam (PF11798) Pfam (PF11799)	Homo sapiens (human)	DINB protein, DINP
2	C, E (P, Q)	5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*A)-3'	polymer	13	4090.7	2
3	D, F (T, U)	5'-D(*TP*TP*CP*CP*(TTD)P*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'	polymer	17	5345.4	2
4	G, J (A, B)	2'-DEOXYADENOSINE 5'-TRIPHOSPHATE	non-polymer		491.2	2	Chemie (DTP)
5	H, I, K, L (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	M, N (A, B)	water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, B: 19 - 528 (UniProt: Q9UBT6)

PDB	External Database	Details
Gly 12	-	expression tag
Pro 13	-	expression tag
Gly 14	-	expression tag
Gly 15	-	expression tag
Asp 16	-	expression tag
Pro 17	-	expression tag
His 18	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	136674.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1079.6
All*	Total formula weight	137754.2

*Water molecules are not included.