2E9R
| Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin | Descriptor: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-01-26 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E9S
| human neuronal Rab6B in three intermediate forms | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NITRATE ION, ... | Authors: | Vellieux, F.M, Tcherniuk, S, Garcia-Saez, I, Kozielski, F. | Deposit date: | 2007-01-26 | Release date: | 2008-01-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | 3D structure of human neuronal Rab6B in three intermediate forms To be Published
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2E9T
| Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP | Descriptor: | 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', 5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-01-26 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E9U
| Structure of h-CHK1 complexed with A780125 | Descriptor: | 18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE, Serine/threonine-protein kinase Chk1 | Authors: | Park, C. | Deposit date: | 2007-01-27 | Release date: | 2008-01-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Design, Synthesis and Biological Evaluation of Potent Selective Macrocyclic Chk1 Inhibitors To be Published
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2E9V
| Structure of h-CHK1 complexed with A859017 | Descriptor: | 18-CHLORO-2-OXO-17-[(PYRIDIN-4-YLMETHYL)AMINO]-2,3,11,12,13,14-HEXAHYDRO-1H,10H-4,8-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECINE-7-CARBONITRILE, Serine/threonine-protein kinase Chk1 | Authors: | Park, C. | Deposit date: | 2007-01-27 | Release date: | 2008-01-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Design, Synthesis and Biological Evaluation of Potent Selective Macrocyclic Chk1 Inhibitors To be Published
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2E9W
| Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor | Authors: | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | Deposit date: | 2007-01-27 | Release date: | 2007-08-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor Cell(Cambridge,Mass.), 130, 2007
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2E9X
| The crystal structure of human GINS core complex | Descriptor: | DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ... | Authors: | Kamada, K, Hanaoka, F. | Deposit date: | 2007-01-27 | Release date: | 2007-04-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the human GINS complex and its assembly and functional interface in replication initiation Nat.Struct.Mol.Biol., 14, 2007
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2E9Y
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2E9Z
| Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP | Descriptor: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-01-29 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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2EA0
| Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli in complex with AP-site containing DNA substrate | Descriptor: | 5'-D(P*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3', Endonuclease VIII, ... | Authors: | Golan, G, Zharov, D.O, Grollman, A.P, Shoham, G. | Deposit date: | 2007-01-29 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrate and mutations of critical residues To be Published
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2EA1
| Crystal structure of Ribonuclease I from Escherichia coli COMPLEXED WITH GUANYLYL-2(PRIME),5(PRIME)-GUANOSINE | Descriptor: | GUANYLYL-2',5'-PHOSPHOGUANOSINE, Ribonuclease I | Authors: | Zhou, K, Pan, J, Padmanabhan, S, Lim, R.W, Lim, L.W. | Deposit date: | 2007-01-29 | Release date: | 2008-01-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Ribonuclease I from Escherichia Coli Complexed with Guanylyl-2(Prime),5(Prime)-Guanosine at 1.80 Angstroms Resolution To be Published
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2EA2
| h-MetAP2 complexed with A773812 | Descriptor: | 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | Authors: | Park, C.H. | Deposit date: | 2007-01-30 | Release date: | 2008-02-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids Bioorg.Med.Chem.Lett., 17, 2007
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2EA3
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2EA4
| h-MetAP2 complexed with A797859 | Descriptor: | 2-(2-AMINOETHOXY)-3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | Authors: | Park, C.H. | Deposit date: | 2007-01-30 | Release date: | 2008-02-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids Bioorg.Med.Chem.Lett., 17, 2007
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2EA5
| Solution Structure of the RING domain of the human Cell growth regulator with RING finger domain 1 protein | Descriptor: | Cell growth regulator with RING finger domain protein 1, ZINC ION | Authors: | Miyamoto, K, Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-30 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of the RING domain of the human Cell growth regulator with RING finger domain 1 protein To be Published
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2EA6
| Solution Structure of the RING domain of the human ring finger protein 4 | Descriptor: | RING finger protein 4, ZINC ION | Authors: | Miyamoto, K, Yoneyama, M, Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-30 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of the RING domain of the human ring finger protein 4 To be Published
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2EA7
| Crystal Structure of Adzuki Bean 7S Globulin-1 | Descriptor: | 7S globulin-1, ACETIC ACID, CALCIUM ION | Authors: | Fukuda, T, Mikami, B, Utsumi, S. | Deposit date: | 2007-01-30 | Release date: | 2008-02-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Characterization and crystallography of recombinant 7S globulins of Adzuki bean and structure-function relationships with 7S globulins of various crops. J.Agric.Food Chem., 56, 2008
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2EA9
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2EAA
| Crystal Structure of Adzuki Bean 7S Globulin-3 | Descriptor: | 7S globulin-3, ACETIC ACID, CALCIUM ION, ... | Authors: | Fukuda, T, Mikami, B, Utsumi, S. | Deposit date: | 2007-01-31 | Release date: | 2008-02-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Characterization and crystallography of recombinant 7S globulins of Adzuki bean and structure-function relationships with 7S globulins of various crops. J.Agric.Food Chem., 56, 2008
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2EAB
| Crystal structure of 1,2-a-L-fucosidase from Bifidobacterium bifidum (apo form) | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-fucosidase, ... | Authors: | Nagae, M, Tsuchiya, A, Katayama, T, Yamamoto, K, Wakatsuki, S, Kato, R. | Deposit date: | 2007-01-31 | Release date: | 2007-04-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Structural basis on the catalytic reaction mechanism of novel 1,2-alpha-L-fucosidase (AFCA) from Bifidobacterium bifidum J.Biol.Chem., 282, 2007
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2EAC
| Crystal structure of 1,2-a-L-fucosidase from Bifidobacterium bifidum in complex with deoxyfuconojirimycin | Descriptor: | (2S,3R,4S,5R)-2-METHYLPIPERIDINE-3,4,5-TRIOL, Alpha-fucosidase, CALCIUM ION | Authors: | Nagae, M, Tsuchiya, A, Katayama, T, Yamamoto, K, Wakatsuki, S, Kato, R. | Deposit date: | 2007-01-31 | Release date: | 2007-04-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis on the catalytic reaction mechanism of novel 1,2-alpha-L-fucosidase (AFCA) from Bifidobacterium bifidum J.Biol.Chem., 282, 2007
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2EAD
| Crystal structure of 1,2-a-L-fucosidase from Bifidobacterium bifidum in complex with substrate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Alpha-fucosidase, CALCIUM ION, ... | Authors: | Nagae, M, Tsuchiya, A, Katayama, T, Yamamoto, K, Wakatsuki, S, Kato, R. | Deposit date: | 2007-01-31 | Release date: | 2007-04-24 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural basis on the catalytic reaction mechanism of novel 1,2-alpha-L-fucosidase (AFCA) from Bifidobacterium bifidum J.Biol.Chem., 282, 2007
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2EAE
| Crystal structure of 1,2-a-L-fucosidase from Bifidobacterium bifidum in complexes with products | Descriptor: | Alpha-fucosidase, CALCIUM ION, alpha-L-fucopyranose, ... | Authors: | Nagae, M, Tsuchiya, A, Katayama, T, Yamamoto, K, Wakatsuki, S, Kato, R. | Deposit date: | 2007-01-31 | Release date: | 2007-04-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis on the catalytic reaction mechanism of novel 1,2-alpha-L-fucosidase (AFCA) from Bifidobacterium bifidum J.Biol.Chem., 282, 2007
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2EAK
| Crystal structure of human galectin-9 N-terminal CRD in complex with lactose | Descriptor: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, Galectin-9, ... | Authors: | Nagae, M, Nakamura-Tsuruta, S, Nishi, N, Nakamura, T, Hirabayashi, J, Wakatsuki, S, Kato, R. | Deposit date: | 2007-01-31 | Release date: | 2007-09-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue. J.Mol.Biol., 375, 2008
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2EAL
| Crystal structure of human galectin-9 N-terminal CRD in complex with Forssman pentasaccharide | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, Galectin-9 | Authors: | Nagae, M, Nakamura-Tsuruta, S, Nishi, N, Nakamura, T, Hirabayashi, J, Wakatsuki, S, Kato, R. | Deposit date: | 2007-01-31 | Release date: | 2007-09-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue. J.Mol.Biol., 375, 2008
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