PDB: 1182 件ウェブページステータス検索Chemie searchBIRD

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8HIX	Cryo-EM structure of GPR21_m5_Gs 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-03-15 最終更新日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HJ2	GPR21 wt with G15 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HJ0	GPR21(m5) and G15 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X. 登録日 2022-11-22 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HJ5	Cryo-EM structure of Gq-coupled MRGPRX1 bound with Compound-16 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... 著者 Gan, B, Yu, L.Y, Ren, R.B. 登録日 2022-11-22 公開日 2023-05-31 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Mechanism of agonist-induced activation of the human itch receptor MRGPRX1. Plos Biol., 21, 2023
8HJ1	GPR21(wt) and Gs complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8F7W	Gi bound kappa-opioid receptor in complex with dynorphin 分子名称: CHOLESTEROL, Dynorphin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7R	Gi bound mu-opioid receptor in complex with endomorphin 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7Q	Gi bound mu-opioid receptor in complex with beta-endorphin 分子名称: Beta-endorphin, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7X	Gi bound nociceptin receptor in complex with nociceptin peptide 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7S	Gi bound delta-opioid receptor in complex with deltorphin 分子名称: CHOLESTEROL, Delta-type opioid receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8HDP	Structure of A2BR bound to endogenous agonists adenosine 分子名称: ADENOSINE, Adenosine A2b receptor, CHOLESTEROL, ... 著者 Cai, H, Xu, Y, Xu, H.E, Jiang, Y. 登録日 2022-11-05 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell Discov, 8, 2022
8HDO	Structure of A2BR bound to synthetic agonists BAY 60-6583 分子名称: 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Adenosine A2b receptor, CHOLESTEROL, ... 著者 Cai, H, Xu, Y, Xu, H.E, Jiang, Y. 登録日 2022-11-05 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell Discov, 8, 2022
8HCX	Cryo-EM structure of Endothelin1-bound ETBR-Gq complex 分子名称: Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. 登録日 2022-11-03 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14, 2023
8HCQ	Cryo-EM structure of endothelin1-bound ETAR-Gq complex 分子名称: Endothelin-1, Endothelin-1 receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. 登録日 2022-11-02 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14, 2023
8HBD	Cryo-EM structure of IRL1620-bound ETBR-Gi complex 分子名称: Endothelin receptor type B,Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Yuan, Q, Ji, Y, Jiang, Y, Duan, J, Xu, H.E. 登録日 2022-10-28 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14, 2023
8H8J	Lodoxamide-bound GPR35 in complex with G13 分子名称: 2,2'-[(2-chloro-5-cyano-1,3-phenylene)bis(azanediyl)]bis(oxoacetic acid), CALCIUM ION, CHOLESTEROL, ... 著者 Yuan, Q, Duan, J, Liu, Q, Xu, H.E, Jiang, Y. 登録日 2022-10-23 公開日 2023-02-08 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Insights into divalent cation regulation and G 13 -coupling of orphan receptor GPR35. Cell Discov, 8, 2022
8H4I	DHA-bound FFAR4 in complex with Gs 分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 He, Y, Yin, H. 登録日 2022-10-10 公開日 2023-06-21 最終更新日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
8H4L	DHA-bound FFAR4 in complex with Gq 分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 He, Y, Yin, H. 登録日 2022-10-10 公開日 2023-06-21 最終更新日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
8H4K	GW9508-bound FFAR4 in complex with Gq 分子名称: 3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 He, Y, Yin, H. 登録日 2022-10-10 公開日 2023-06-21 最終更新日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
8H2G	Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Park, J.H, Ishimoto, N, Park, S.Y. 登録日 2022-10-06 公開日 2023-10-11 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural basis for hydroxy-carboxylic acid receptor 2 activation and allosteric mechanism To Be Published
8H0P	Structure of the NMB30-NMBR and Gq complex 分子名称: G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Li, C, Xu, Y, Liu, H, Cai, H, Xu, H.E, Yin, W. 登録日 2022-09-30 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Molecular recognition of itch-associated neuropeptides by bombesin receptors Cell Res., 33, 2023
8H0Q	Structure of the GRP14-27-GRPR-Gq complex 分子名称: CHOLESTEROL, G-alpha q, GRP, ... 著者 Li, C, Xu, Y, Liu, H, Cai, H, Xu, H.E, Yin, W. 登録日 2022-09-30 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular recognition of itch-associated neuropeptides by bombesin receptors Cell Res., 33, 2023
8GY7	Cryo-EM structure of ACTH-bound melanocortin-2 receptor in complex with MRAP1 and Gs protein 分子名称: CALCIUM ION, Corticotropin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Luo, P, Feng, W.B, Ma, S.S, Dai, A.T, Yuan, Q.N, Wu, K, Yang, D.H, Wang, M.W, Xu, H.E, Jiang, Y. 登録日 2022-09-21 公開日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of signaling regulation of the human melanocortin-2 receptor by MRAP1. Cell Res., 33, 2023
8EJK	Structure of FFAR1-Gq complex bound to TAK-875 in a lipid nanodisc 分子名称: A modified Guanine nucleotide-binding protein G(q) subunit alpha, Free fatty acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Kumari, P, Inoue, A, Chapman, K, Lian, P, Rosenbaum, D.M. 登録日 2022-09-17 公開日 2023-05-24 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular mechanism of fatty acid activation of FFAR1. Proc.Natl.Acad.Sci.USA, 120, 2023
8EJC	Structure of FFAR1-Gq complex bound to TAK-875 分子名称: A modified Guanine nucleotide-binding protein G(q) subunit alpha, Free fatty acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Kumari, P, Inoue, A, Chapman, K, Lian, P, Rosenbaum, D.M. 登録日 2022-09-16 公開日 2023-05-24 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular mechanism of fatty acid activation of FFAR1. Proc.Natl.Acad.Sci.USA, 120, 2023

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