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7QV5
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BU of 7qv5 by Molmil
Amyloid fibril from the antimicrobial peptide uperin 3.5
Descriptor: Uperin-3.5
Authors:Buecker, R, Seuring, C, Cazey, C, Veith, K, Garcia-Alai, M, Gruenewald, K, Landau, M.
Deposit date:2022-01-19
Release date:2022-06-29
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The Cryo-EM structures of two amphibian antimicrobial cross-beta amyloid fibrils.
Nat Commun, 13, 2022
8H2J
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BU of 8h2j by Molmil
Structure of Acb2 complexed with 3',3'-cGAMP
Descriptor: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, p26
Authors:Feng, Y, Cao, X.L.
Deposit date:2022-10-06
Release date:2023-02-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Bacteriophages inhibit and evade cGAS-like immune function in bacteria.
Cell, 186, 2023
5NRH
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BU of 5nrh by Molmil
Crystal structure of Burkholderia pseudomallei D-alanine-D-alanine ligase in complex with AMP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, D-alanine--D-alanine ligase, ...
Authors:Diaz-Saez, L, Hunter, W.N.
Deposit date:2017-04-23
Release date:2018-05-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Burkholderia pseudomallei d-alanine-d-alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target.
Febs J., 2019
5NRI
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BU of 5nri by Molmil
Crystal structure of Burkholderia pseudomallei D-alanine-D-alanine ligase in complex with AMP and D-Ala-D-Ala
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, D-ALANINE, ...
Authors:Diaz-Saez, L, Hunter, W.N.
Deposit date:2017-04-23
Release date:2018-05-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Burkholderia pseudomallei d-alanine-d-alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target.
Febs J., 2019
4D7A
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BU of 4d7a by Molmil
Crystal structure of E. coli tRNA N6-threonylcarbamoyladenosine dehydratase, TcdA, in complex with AMP at 1.801 Angstroem resolution
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCEROL, PHOSPHATE ION, ...
Authors:Lopez-Estepa, M, Arda, A, Savko, M, Round, A, Shepard, W, Bruix, M, Coll, M, Fernandez, F.J, Jimenez-Barbero, J, Vega, M.C.
Deposit date:2014-11-21
Release date:2015-05-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:The Crystal Structure and Small-Angle X-Ray Analysis of Csdl/Tcda Reveal a New tRNA Binding Motif in the Moeb/E1 Superfamily.
Plos One, 10, 2015
7MP9
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BU of 7mp9 by Molmil
Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 phosphorylated at Ser205 in complex with ADP analog
Descriptor: AMP PHOSPHORAMIDATE, MAGNESIUM ION, SULFATE ION, ...
Authors:Rasool, S, Veyron, S, Trempe, J.F.
Deposit date:2021-05-04
Release date:2021-12-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex.
Mol.Cell, 82, 2022
3RK0
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BU of 3rk0 by Molmil
X-ray crystal Structure of the putative N-type ATP pyrophosphatase (PF0828) in complex with AMP from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR23
Descriptor: ADENOSINE MONOPHOSPHATE, N-type ATP pyrophosphatase superfamily
Authors:Forouhar, F, Saadat, N, Hussain, M, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-04-16
Release date:2011-05-11
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding.
Acta Crystallogr.,Sect.F, 67, 2011
7LT2
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BU of 7lt2 by Molmil
Structure of a dsRNA-sensing cGAS-like receptor from the beetle Tribolium castaneum
Descriptor: MANGANESE (II) ION, Mab-21 domain-containing protein
Authors:Slavik, K.M, Morehouse, B.R, Kranzusch, P.J.
Deposit date:2021-02-18
Release date:2021-07-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
8H53
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BU of 8h53 by Molmil
Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
Descriptor: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
Authors:Park, J.S, Han, B.W.
Deposit date:2022-10-12
Release date:2023-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
6RRL
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BU of 6rrl by Molmil
Solution NMR structure of the peptide 3967 from medicinal leech Hirudo medicinalis in dodecylphosphocholine micelles
Descriptor: peptide 3967
Authors:Nadezhdin, K.D, Grafskaia, E.N, Arseniev, A.S, Lazarev, V.N.
Deposit date:2019-05-20
Release date:2019-07-24
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
6RSM
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BU of 6rsm by Molmil
Solution NMR structure of the peptide 12530 from medicinal leech Hirudo medicinalis in dodecylphosphocholine micelles
Descriptor: peptide 12530
Authors:Talyzina, I.A, Nadezhdin, K.D, Grafskaia, E.N, Arseniev, A.S, Lazarev, V.N.
Deposit date:2019-05-21
Release date:2019-07-24
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
7ELT
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BU of 7elt by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Trp-AMP
Descriptor: TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase
Authors:Xu, M, Chen, S.
Deposit date:2021-04-12
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7DU3
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BU of 7du3 by Molmil
ThiL in complex with AMP-PNP
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Lin, J.Q, Lescar, J.
Deposit date:2021-01-07
Release date:2022-03-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:ThiL in complex with AMP-PNP
To Be Published
4BLW
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BU of 4blw by Molmil
Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ in complex with S-adenosylhomocysteine (AdoHcy) and Adenosine monophosphate (AMP)
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, GLYCEROL, ...
Authors:Punekar, A.S, Liljeruhm, J, Shepherd, T.R, Forster, A.C, Selmer, M.
Deposit date:2013-05-04
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.
Nucleic Acids Res., 41, 2013
6RRO
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BU of 6rro by Molmil
Solution NMR structure of the peptide 536_2 from medicinal leech Hirudo medicinalis in dodecylphosphocholine micelles
Descriptor: peptide 536_2
Authors:Nadezhdin, K.D, Grafskaia, E.N, Arseniev, A.S, Lazarev, V.N.
Deposit date:2019-05-20
Release date:2019-07-24
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
7FEW
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BU of 7few by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF0
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BU of 7ff0 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF8
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BU of 7ff8 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7FF9
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BU of 7ff9 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-23
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
8W6P
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BU of 8w6p by Molmil
Crystal structure of dimeric murine SMPDL3A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
Authors:Zhang, C, Liu, P, Fan, S, Hou, Y.
Deposit date:2023-08-29
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
8W6R
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BU of 8w6r by Molmil
murine SMPDL3A bound to sulfate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
Authors:Zhang, C, Liu, P, Fan, S.
Deposit date:2023-08-29
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
1QUE
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BU of 1que by Molmil
X-RAY STRUCTURE OF THE FERREDOXIN:NADP+ REDUCTASE FROM THE CYANOBACTERIUM ANABAENA PCC 7119 AT 1.8 ANGSTROMS
Descriptor: FERREDOXIN--NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Serre, L, Frey, M, Vellieux, F.M.D.
Deposit date:1996-07-06
Release date:1997-05-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure of the ferredoxin:NADP+ reductase from the cyanobacterium Anabaena PCC 7119 at 1.8 A resolution, and crystallographic studies of NADP+ binding at 2.25 A resolution.
J.Mol.Biol., 263, 1996
1QUF
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BU of 1quf by Molmil
X-RAY STRUCTURE OF A COMPLEX NADP+-FERREDOXIN:NADP+ REDUCTASE FROM THE CYANOBACTERIUM ANABAENA PCC 7119 AT 2.25 ANGSTROMS
Descriptor: FERREDOXIN-NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Serre, L, Frey, M, Vellieux, F.M.D.
Deposit date:1996-09-07
Release date:1997-09-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:X-ray structure of the ferredoxin:NADP+ reductase from the cyanobacterium Anabaena PCC 7119 at 1.8 A resolution, and crystallographic studies of NADP+ binding at 2.25 A resolution.
J.Mol.Biol., 263, 1996
5SVB
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BU of 5svb by Molmil
Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase AMP bound structure
Descriptor: ADENOSINE MONOPHOSPHATE, Acetone carboxylase alpha subunit, Acetone carboxylase beta subunit, ...
Authors:Eilers, B.J, Mus, F, Alleman, A.B, Kabasakal, B.V, Murray, J.W, Nocek, B.P, Dubois, J.L, Peters, J.W.
Deposit date:2016-08-05
Release date:2017-08-09
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.645 Å)
Cite:Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation.
Sci Rep, 7, 2017
8UCI
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BU of 8uci by Molmil
Thermophilic RNA Ligase from Palaeococcus pacificus K238G + AMP
Descriptor: ADENOSINE MONOPHOSPHATE, ATP dependent DNA ligase, GLYCEROL, ...
Authors:Rousseau, M.D, Hicks, J.L, Oulavallickal, T, Williamson, A, Arcus, V.L, Patrick, M.W.
Deposit date:2023-09-26
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus.
Nucleic Acids Res., 52, 2024

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