6DNK

Human Stimulator of Interferon Genes

Summary for 6DNK

Entry DOI	10.2210/pdb6dnk/pdb
Descriptor	Stimulator of interferon genes protein, cGAMP (3 entities in total)
Functional Keywords	human sting, complex, 2', 3'-cgamp, tmem173, ala230 allelle, 230a/232r, immune system
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	21772.13
Authors	Fernandez, D.,Li, L.,Ergun, S.L. (deposition date: 2018-06-06, release date: 2019-03-13, Last modification date: 2023-10-11)
Primary citation	Ergun, S.L.,Fernandez, D.,Weiss, T.M.,Li, L. STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition. Cell, 178:290-301.e10, 2019 Cited by PubMed: 31230712 DOI: 10.1016/j.cell.2019.05.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation