8UU4
 
 | | Cryo-EM structure of the Listeria innocua 70S ribosome in complex with HPF (structure I-A) | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... | | Authors: | Seely, S.M, Basu, R.S, Gagnon, M.G. | | Deposit date: | 2023-10-31 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Mechanistic insights into the alternative ribosome recycling by HflXr.
Nucleic Acids Res., 52, 2024
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8UU6
 | | Cryo-EM structure of the ratcheted Listeria innocua 70S ribosome in complex with p/E-tRNA (structure II-A) | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... | | Authors: | Seely, S.M, Basu, R.S, Gagnon, M.G. | | Deposit date: | 2023-10-31 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Mechanistic insights into the alternative ribosome recycling by HflXr.
Nucleic Acids Res., 52, 2024
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8UU7
 | | Cryo-EM structure of the Listeria innocua 70S ribosome in complex with HflXr, HPF, and E-site tRNA (structure II-B) | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... | | Authors: | Seely, S.M, Basu, R.S, Gagnon, M.G. | | Deposit date: | 2023-10-31 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mechanistic insights into the alternative ribosome recycling by HflXr.
Nucleic Acids Res., 52, 2024
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8WQ2
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8WQ4
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8XXL
 | | Cryo-EM structure of the human 40S ribosome with PDCD4 | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | Deposit date: | 2024-01-18 | | Release date: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 2024
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8XXM
 | | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | Deposit date: | 2024-01-18 | | Release date: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 2024
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8XXN
 | | Cryo-EM structure of the human 43S ribosome with PDCD4 | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | Deposit date: | 2024-01-18 | | Release date: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 2024
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8VS9
 | | Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site and deacyl-tRNA in the E site of E. coli 70S ribosome | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Teran, D, Zhang, Y, Korostelev, A.A. | | Deposit date: | 2024-01-23 | | Release date: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon.
Front Microbiol, 15, 2024
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8VSA
 | | Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site of E. coli 70S ribosome | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Teran, D, Zhang, Y, Korostelev, A.A. | | Deposit date: | 2024-01-23 | | Release date: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon.
Front Microbiol, 15, 2024
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8Y0W
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8Y0X
 | | Dormant ribosome with SERBP1 | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Du, M, Zeng, F. | | Deposit date: | 2024-01-23 | | Release date: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The global structure of dormant ribosome
To Be Published
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8WI7
 | | Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, bS1 and RafH. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | | Deposit date: | 2023-09-24 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
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8WIF
 | | Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome and RafH. | | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | | Deposit date: | 2023-09-24 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
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8WID
 | | Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome, E- tRNA and RafH. | | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | | Deposit date: | 2023-09-24 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
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8WHX
 | | Cryo- EM structure of Mycobacterium smegmatis 70S ribosome and RafH. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | | Deposit date: | 2023-09-23 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
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8WI9
 | | Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome, bS1 and RafH. | | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | | Deposit date: | 2023-09-24 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
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8WIB
 | | Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, E- tRNA and RafH. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | | Deposit date: | 2023-09-24 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
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8V9J
 | | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) (Structure 4) | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S14, ... | | Authors: | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | | Deposit date: | 2023-12-08 | | Release date: | 2024-02-07 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
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8V9L
 | | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | | Authors: | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | | Deposit date: | 2023-12-08 | | Release date: | 2024-02-07 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
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8WKP
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8V9K
 | | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Rv2629 (Balon) (Structure 5) | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | | Authors: | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | | Deposit date: | 2023-12-08 | | Release date: | 2024-02-07 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
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8UD6
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution | | Descriptor: | (4S,5aS,8S,8aR)-4-(2-methylpropyl)-N-[(1R,5Z,7R,8R,9R,10R,11S,12R)-10,11,12-trihydroxy-7-methyl-13-oxa-2-thiabicyclo[7.3.1]tridec-5-en-8-yl]octahydro-2H-oxepino[2,3-c]pyrrole-8-carboxamide (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | Authors: | Aleksandrova, E.V, Syroegin, E.A, Wu, K.J.Y, Tresco, B.I.C, Ramkissoon, A, See, D.N.Y, Liow, P, Dittemore, G.A, Yu, M, Testolin, G, Mitcheltree, M.J, Liu, R.Y, Svetlov, M.S, Myers, A.G, Polikanov, Y.S. | | Deposit date: | 2023-09-28 | | Release date: | 2024-02-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance.
Science, 383, 2024
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8UD8
 | | Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution | | Descriptor: | (4S,5aS,8S,8aR)-4-(2-methylpropyl)-N-[(1R,5Z,7R,8R,9R,10R,11S,12R)-10,11,12-trihydroxy-7-methyl-13-oxa-2-thiabicyclo[7.3.1]tridec-5-en-8-yl]octahydro-2H-oxepino[2,3-c]pyrrole-8-carboxamide (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | Authors: | Aleksandrova, E.V, Syroegin, E.A, Wu, K.J.Y, Tresco, B.I.C, Ramkissoon, A, See, D.N.Y, Liow, P, Dittemore, G.A, Yu, M, Testolin, G, Mitcheltree, M.J, Liu, R.Y, Svetlov, M.S, Myers, A.G, Polikanov, Y.S. | | Deposit date: | 2023-09-28 | | Release date: | 2024-02-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance.
Science, 383, 2024
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8UD7
 | | Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution | | Descriptor: | (4S,5aS,8S,8aR)-4-(2-methylpropyl)-N-[(1R,5Z,7R,8R,9R,10R,11S,12R)-10,11,12-trihydroxy-7-methyl-13-oxa-2-thiabicyclo[7.3.1]tridec-5-en-8-yl]octahydro-2H-oxepino[2,3-c]pyrrole-8-carboxamide (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | Authors: | Aleksandrova, E.V, Syroegin, E.A, Wu, K.J.Y, Tresco, B.I.C, Ramkissoon, A, See, D.N.Y, Liow, P, Dittemore, G.A, Yu, M, Testolin, G, Mitcheltree, M.J, Liu, R.Y, Svetlov, M.S, Myers, A.G, Polikanov, Y.S. | | Deposit date: | 2023-09-28 | | Release date: | 2024-02-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance.
Science, 383, 2024
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