8ORG
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8OPI
| VHH Z70 mutant 1 in interaction with PHF6 Tau peptide | Descriptor: | PHF6 Tau peptide, VHH Z70 mutant 1 | Authors: | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | Deposit date: | 2023-04-07 | Release date: | 2023-05-31 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300, 2024
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8OP0
| VHH Z70 mutant 20 in interaction with PHF6 Tau peptide | Descriptor: | Tau PHF6 peptide, VHH Z70 mutant 20 | Authors: | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | Deposit date: | 2023-04-06 | Release date: | 2023-05-31 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300, 2024
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3OVL
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6XLI
| CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE | Descriptor: | GLYCEROL, PT3 Fab Heavy Chain, PT3 Fab Light Chain, ... | Authors: | Malia, T.J, Teplyakov, A, Luo, J. | Deposit date: | 2020-06-28 | Release date: | 2020-09-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody. J Alzheimers Dis, 77, 2020
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1I8H
| SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH HUMAN TAU PHOSPHOTHREONINE PEPTIDE | Descriptor: | MICROTUBULE-ASSOCIATED PROTEIN TAU, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | Authors: | Wintjens, R, Wieruszeski, J.-M, Drobecq, H, Lippens, G, Landrieu, I. | Deposit date: | 2001-03-14 | Release date: | 2001-07-18 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | 1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides. J.Biol.Chem., 276, 2001
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2MZ7
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9BBL
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9BBM
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4NP8
| Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph) | Descriptor: | Microtubule-associated protein tau | Authors: | Landau, M, Eisenberg, D, Sawaya, M.R, Dannenberg, J, Kobko, N. | Deposit date: | 2013-11-20 | Release date: | 2013-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Molecular mechanisms for protein-encoded inheritance. Nat.Struct.Mol.Biol., 16, 2009
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5V5B
| KVQIINKKLD, Structure of the amyloid spine from microtubule associated protein tau Repeat 2 | Descriptor: | Microtubule-associated protein tau | Authors: | Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R. | Deposit date: | 2017-03-13 | Release date: | 2018-02-07 | Last modified: | 2024-03-13 | Method: | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | Cite: | Structure-based inhibitors of tau aggregation. Nat Chem, 10, 2018
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8Q2J
| Tau - AD-MIA2 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-02 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q7F
| Tau - AD-MIA5 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-16 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q88
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8Q27
| Tau: AD-MIA1 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D. | Deposit date: | 2023-08-01 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.02 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q7L
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8Q7M
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8Q9G
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8QCP
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8QCR
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8Q2K
| Tau - AD-MIA3 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-02 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q7T
| Tau - AD-MIA11 | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | Deposit date: | 2023-08-17 | Release date: | 2023-08-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8Q8D
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8Q8C
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8Q7P
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