3OVL

Structure of an amyloid forming peptide VQIVYK from the TAU protein in complex with orange G

Summary for 3OVL

Entry DOI	10.2210/pdb3ovl/pdb
Related	2ON9 3FQP
Descriptor	Microtubule-associated protein, ZINC ION, ACETIC ACID, ... (5 entities in total)
Functional Keywords	amyloid-like protofibril in complex with a small-molecule binder, protein fibril
Cellular location	Cytoplasm, cytosol: P10636
Total number of polymer chains	1
Total formula weight	1349.19
Authors	Landau, M.,Eisenberg, D. (deposition date: 2010-09-16, release date: 2011-07-06, Last modification date: 2024-02-21)
Primary citation	Landau, M.,Sawaya, M.R.,Faull, K.F.,Laganowsky, A.,Jiang, L.,Sievers, S.A.,Liu, J.,Barrio, J.R.,Eisenberg, D. Towards a pharmacophore for amyloid. Plos Biol., 9:e1001080-e1001080, 2011 Cited by PubMed: 21695112 DOI: 10.1371/journal.pbio.1001080 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation