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PDB: 189 results

3SL1
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BU of 3sl1 by Molmil
Crystal Structure of P. falciparum arginase complexed with 2-amino-6-borono-2-methylhexanoic acid
Descriptor: 6-(dihydroxyboranyl)-2-methyl-L-norleucine, Arginase, MANGANESE (II) ION
Authors:Dowling, D.P, Ilies, M, Christianson, D.W.
Deposit date:2011-06-23
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
3SL0
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BU of 3sl0 by Molmil
Crystal Structure of P. falciparum arginase complexed with 2-amino-6-borono-2-(difluoromethyl)hexanoic acid
Descriptor: 2-(difluoromethyl)-6-(dihydroxyboranyl)-L-norleucine, Arginase, MANGANESE (II) ION
Authors:Dowling, D.P, Ilies, M, Christianson, D.W.
Deposit date:2011-06-23
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
3SKK
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BU of 3skk by Molmil
Crystal structure of human arginase I in complex with the inhibitor FABH, Resolution 1.70 A, twinned structure
Descriptor: Arginase-1, MANGANESE (II) ION, [(5S)-5-amino-5-carboxy-6,6-difluorohexyl](trihydroxy)borate(1-)
Authors:Thorn, K.J, Di Costanzo, L, Christianson, D.W.
Deposit date:2011-06-22
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
3SJT
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BU of 3sjt by Molmil
Crystal structure of human arginase I in complex with the inhibitor Me-ABH, Resolution 1.60 A, twinned structure
Descriptor: Arginase-1, MANGANESE (II) ION, [(5S)-5-amino-5-carboxyhexyl](trihydroxy)borate
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2011-06-21
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.597 Å)
Cite:Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
3THH
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BU of 3thh by Molmil
Crystal structure of the Co2+2-HAI-ABH complex
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, COBALT (II) ION
Authors:D'Antonio, E.L, Christianson, D.W.
Deposit date:2011-08-19
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of complexes with cobalt-reconstituted human arginase I.
Biochemistry, 50, 2011
3THE
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BU of 3the by Molmil
Crystal structure of Co2+2-HAI (pH 8.5)
Descriptor: Arginase-1, BICINE, COBALT (II) ION
Authors:D'Antonio, E.L, Christianson, D.W.
Deposit date:2011-08-18
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structures of complexes with cobalt-reconstituted human arginase I.
Biochemistry, 50, 2011
3TF3
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BU of 3tf3 by Molmil
Crystal structure of metal-free Human Arginase I
Descriptor: Arginase-1
Authors:D'Antonio, E.L, Christianson, D.W.
Deposit date:2011-08-15
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal structures of complexes with cobalt-reconstituted human arginase I.
Biochemistry, 50, 2011
3TH7
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BU of 3th7 by Molmil
Crystal structure of unliganded Co2+2-HAI (pH 7.0)
Descriptor: Arginase-1, COBALT (II) ION
Authors:D'Antonio, E.L, Christianson, D.W.
Deposit date:2011-08-18
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of complexes with cobalt-reconstituted human arginase I.
Biochemistry, 50, 2011
3THJ
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BU of 3thj by Molmil
Crystal structure of the Co2+2-HAI-L-Orn complex
Descriptor: Arginase-1, COBALT (II) ION, L-ornithine
Authors:D'Antonio, E.L, Christianson, D.W.
Deposit date:2011-08-19
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of complexes with cobalt-reconstituted human arginase I.
Biochemistry, 50, 2011
3KV2
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BU of 3kv2 by Molmil
HIGH RESOLUTION STRUCTURE OF HUMAN ARGINASE I IN COMPLEX WITH THE STRONG INHIBITOR N(omega)-hydroxy-nor-L-arginine (nor-NOHA)
Descriptor: Arginase-1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2009-11-28
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
3LHL
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BU of 3lhl by Molmil
Crystal structure of a putative agmatinase from Clostridium difficile
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-01-22
Release date:2010-02-23
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a putative agmatinase from Clostridium difficile
To be Published
3LP7
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BU of 3lp7 by Molmil
Crystal structure of Human Arginase I in complex with inhibitor N(omega)-hydroxy-L-arginine (NOHA), 2.04A Resolution
Descriptor: Arginase-1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-02-04
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
3LP4
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BU of 3lp4 by Molmil
Crystal structure of human arginase I in complex with L-LYSINE, 1.90A Resolution.
Descriptor: Arginase-1, LYSINE, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-02-04
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
3M1R
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BU of 3m1r by Molmil
The crystal structure of formimidoylglutamase from Bacillus subtilis subsp. subtilis str. 168
Descriptor: CACODYLATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Tan, K, Bigelow, L, Trevino, D, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-03-05
Release date:2010-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:The crystal structure of formimidoylglutamase from Bacillus subtilis subsp. subtilis str. 168
To be Published
3MFV
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BU of 3mfv by Molmil
Crystal structure of human arginase I in complex with 2-aminohomohistidine
Descriptor: (2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic acid, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-04-04
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
J.Med.Chem., 53, 2010
3MFW
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BU of 3mfw by Molmil
Crystal structure of human arginase I in complex with L-2-aminohistidine and sulphate
Descriptor: 2-amino-L-histidine, Arginase-1, MANGANESE (II) ION, ...
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-04-04
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
J.Med.Chem., 53, 2010
3MMR
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BU of 3mmr by Molmil
Structure of Plasmodium falciparum Arginase in complex with ABH
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase, BETA-MERCAPTOETHANOL, ...
Authors:Dowling, D.P, Ilies, M, Olszewski, K.L, Portugal, S, Mota, M.M, Llinas, M, Christianson, D.W.
Deposit date:2010-04-20
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Biochemistry, 49, 2010
3MJL
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BU of 3mjl by Molmil
Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
Descriptor: 1H-imidazol-2-amine, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-04-13
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
To be Published
3NIO
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BU of 3nio by Molmil
Crystal structure of Pseudomonas aeruginosa guanidinobutyrase
Descriptor: Guanidinobutyrase, MANGANESE (II) ION
Authors:Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Jang, J.Y, Im, H, An, D, Suh, S.W.
Deposit date:2010-06-16
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of Pseudomonas aeruginosa guanidinobutyrase and guanidinopropionase, members of the ureohydrolase superfamily
J.Struct.Biol., 175, 2011
3NIP
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BU of 3nip by Molmil
Crystal structure of Pseudomonas aeruginosa guanidinopropionase complexed with 1,6-diaminohexane
Descriptor: 3-guanidinopropionase, HEXANE-1,6-DIAMINE
Authors:Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Jang, J.Y, Im, H, An, D, Suh, S.W.
Deposit date:2010-06-16
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of Pseudomonas aeruginosa guanidinobutyrase and guanidinopropionase, members of the ureohydrolase superfamily
J.Struct.Biol., 175, 2011
3NIQ
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BU of 3niq by Molmil
Crystal structure of Pseudomonas aeruginosa guanidinopropionase
Descriptor: 3-guanidinopropionase, GLYCEROL, MANGANESE (II) ION
Authors:Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Jang, J.Y, Im, H, An, D, Suh, S.W.
Deposit date:2010-06-16
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structures of Pseudomonas aeruginosa guanidinobutyrase and guanidinopropionase, members of the ureohydrolase superfamily
J.Struct.Biol., 175, 2011
1P8N
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BU of 1p8n by Molmil
Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
Descriptor: Arginase 1, GLYCEROL, MANGANESE (II) ION
Authors:Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
Deposit date:2003-05-07
Release date:2003-06-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003
1P8O
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BU of 1p8o by Molmil
Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
Descriptor: Arginase 1, MANGANESE (II) ION
Authors:Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
Deposit date:2003-05-07
Release date:2003-06-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003
1PQ3
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BU of 1pq3 by Molmil
Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal
Descriptor: Arginase II, mitochondrial precursor, CHLORIDE ION, ...
Authors:Cama, E, Colleluori, D.M, Emig, F.A, Shin, H, Kim, S.W, Kim, N.N, Traish, A.M, Ash, D.E, Christianson, D.W.
Deposit date:2003-06-17
Release date:2003-08-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal
Biochemistry, 42, 2003
1R1O
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BU of 1r1o by Molmil
Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase
Descriptor: Arginase 1, MANGANESE (II) ION, S-[2-(AMINOSULFONYL)ETHYL]-D-CYSTEINE
Authors:Cama, E, Shin, H, Christianson, D.W.
Deposit date:2003-09-24
Release date:2003-10-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Design of Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase
J.Am.Chem.Soc., 125, 2003

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