1R1O

Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase

Summary for 1R1O

Entry DOI	10.2210/pdb1r1o/pdb
Related	1D3V 1HQ5
Descriptor	Arginase 1, MANGANESE (II) ION, S-[2-(AMINOSULFONYL)ETHYL]-D-CYSTEINE, ... (4 entities in total)
Functional Keywords	arginase, hydrolase, sulfonamides, transition-state analogue
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Cytoplasm: P07824
Total number of polymer chains	3
Total formula weight	106071.79
Authors	Cama, E.,Shin, H.,Christianson, D.W. (deposition date: 2003-09-24, release date: 2003-10-28, Last modification date: 2024-02-14)
Primary citation	Cama, E.,Shin, H.,Christianson, D.W. Design of Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase J.Am.Chem.Soc., 125:13052-13057, 2003 Cited by PubMed: 14570477 DOI: 10.1021/ja036365b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation