3LP4
Crystal structure of human arginase I in complex with L-LYSINE, 1.90A Resolution.
Summary for 3LP4
| Entry DOI | 10.2210/pdb3lp4/pdb |
| Related | 2ZAV 3LP7 5CEV |
| Descriptor | Arginase-1, MANGANESE (II) ION, LYSINE, ... (4 entities in total) |
| Functional Keywords | lysine inhibition, manganese cluster, arginine metabolism, cytoplasm, hydrolase, manganese, metal-binding, urea cycle |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P05089 |
| Total number of polymer chains | 2 |
| Total formula weight | 70073.90 |
| Authors | Di Costanzo, L.,Christianson, D.W. (deposition date: 2010-02-04, release date: 2010-02-23, Last modification date: 2023-09-06) |
| Primary citation | Di Costanzo, L.,Ilies, M.,Thorn, K.J.,Christianson, D.W. Inhibition of human arginase I by substrate and product analogues. Arch.Biochem.Biophys., 496:101-108, 2010 Cited by PubMed: 20153713DOI: 10.1016/j.abb.2010.02.004 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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