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PDB: 115 results

3REX
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Crystal structure of the archaeal asparagine synthetase A complexed with Adenosine monophosphate
Descriptor: ADENOSINE MONOPHOSPHATE, AsnS-like asparaginyl-tRNA synthetase related protein, MAGNESIUM ION
Authors:Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
Deposit date:2011-04-05
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3RL6
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Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine and Adenosine monophosphate
Descriptor: ADENOSINE MONOPHOSPHATE, ASPARAGINE, Archaeal asparagine synthetase A, ...
Authors:Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
Deposit date:2011-04-19
Release date:2011-08-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3REU
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BU of 3reu by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid and Adenosine triphosphate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein, ...
Authors:Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
Deposit date:2011-04-05
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3A5Y
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BU of 3a5y by Molmil
Crystal structure of GenX from Escherichia coli in complex with lysyladenylate analog
Descriptor: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Putative lysyl-tRNA synthetase
Authors:Sumida, T, Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2009-08-17
Release date:2010-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P.
Nat.Struct.Mol.Biol., 17, 2010
3G1Z
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Structure of IDP01693/yjeA, a potential t-RNA synthetase from Salmonella typhimurium
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PHOSPHATE ION, ...
Authors:Singer, A.U, Evdokimova, E, Kudritska, M, Cuff, M.E, Edwards, A.M, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-01-30
Release date:2009-03-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica.
Mol.Cell, 39, 2010
1NNH
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Hypothetical protein from Pyrococcus furiosus Pfu-1801964
Descriptor: SODIUM ION, asparaginyl-tRNA synthetase-related peptide
Authors:Tempel, W, Liu, Z.-J, Schubot, F.D, Shah, A, Arendall III, W.B, Rose, J.P, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-01-13
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Hypothetical protein from Pyrococcus furiosus Pfu-1801964
To be published
3P8Y
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Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine
Descriptor: ASPARAGINE, AsnS-like asparaginyl-tRNA synthetase related protein
Authors:Blaise, M, Kern, D.
Deposit date:2010-10-15
Release date:2011-08-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3P8T
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BU of 3p8t by Molmil
Crystal structure of the archaeal asparagine synthetase A
Descriptor: AsnS-like asparaginyl-tRNA synthetase related protein
Authors:Blaise, M, Kern, D.
Deposit date:2010-10-15
Release date:2011-08-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3P8V
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BU of 3p8v by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid
Descriptor: ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein
Authors:Blaise, M, Kern, D.
Deposit date:2010-10-15
Release date:2011-08-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
7ZOG
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BU of 7zog by Molmil
Crystal structure of Cryptosporidium parvum -Plasmodium falciparum mutant lysyl tRNA synthetase in complex with inhibitor
Descriptor: 8-[[4-[2-[2-[2-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]sulfonylamino]-~{N}-(cyclohexylmethyl)-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide, GLYCEROL, LYSINE, ...
Authors:Dawson, A, Wyllie, S.
Deposit date:2022-04-25
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
Acs Infect Dis., 8, 2022
6SJC
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Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine
Descriptor: 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2019-08-13
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
8H53
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BU of 8h53 by Molmil
Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
Descriptor: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
Authors:Park, J.S, Han, B.W.
Deposit date:2022-10-12
Release date:2023-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
4AH6
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Human mitochondrial aspartyl-tRNA synthetase
Descriptor: ASPARTATE--TRNA LIGASE, MITOCHONDRIAL
Authors:Neuenfeldt, A, Sissler, M, Lorber, B, Florentz, C, Sauter, C.
Deposit date:2012-02-03
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Thermodynamic Properties Distinguish Human Mitochondrial Aspartyl-tRNA Synthetase from Bacterial Homolog with Same 3D Architecture
Nucleic Acids Res., 41, 2013
6C86
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Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-24
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
to be published
4UP9
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Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, LYSINE--TRNA LIGASE
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.047 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UP8
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Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase apo form
Descriptor: LYSINE--TRNA LIGASE
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
6CHD
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BU of 6chd by Molmil
Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, ...
Authors:Dranow, D.M, Abendroth, J, Lorimer, D.D.
Deposit date:2018-02-22
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
to be published
6OD8
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Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Putative aspartyl-tRNA synthetase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-03-26
Release date:2019-04-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
to be published
6WBD
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BU of 6wbd by Molmil
Crystal Structure of Lysyl-tRNA synthetase from Stenotrophomonas maltophilia with bound L-lysine
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, LYSINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-03-26
Release date:2020-04-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of Lysyl-tRNA synthetase from Stenotrophomonas maltophilia with bound L-lysine
to be published
4J15
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BU of 4j15 by Molmil
Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex
Descriptor: Aspartate--tRNA ligase, cytoplasmic, GLYCEROL
Authors:Kim, K.R, Park, S.H, Kim, H.S, Kim, B.-G, Kim, D.G, Rhee, K.H, Park, M.S, Kim, H.-J, Kim, S, Han, B.W.
Deposit date:2013-02-01
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex
Proteins, 81, 2013
6PQH
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Crystal structure of Asparagine-tRNA ligase from Elizabethkingia sp. CCUG 26117
Descriptor: 1,2-ETHANEDIOL, Asparagine--tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-07-09
Release date:2019-07-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Asparagine-tRNA ligase from Elizabethkingia sp. CCUG 26117
TO BE PUBLISHED
1G51
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ASPARTYL TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.4 A RESOLUTION
Descriptor: ADENOSINE MONOPHOSPHATE, ASPARTYL-ADENOSINE-5'-MONOPHOSPHATE, ASPARTYL-TRNA SYNTHETASE, ...
Authors:Poterzsman, A, Delarue, M, Thierry, J.C, Moras, D.
Deposit date:2000-10-30
Release date:2000-12-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis and recognition of aspartyl-adenylate by Thermus thermophilus aspartyl-tRNA synthetase.
J.Mol.Biol., 244, 1994
6WOM
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Crystal structure of Aspartyl-tRNA ligase from Elizabethkingia sp.
Descriptor: Aspartate--tRNA ligase, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-24
Release date:2020-05-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of Aspartyl-tRNA ligase from Elizabethkingia sp.
TO BE PUBLISHED
7AP4
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Thermus thermophilus Aspartyl-tRNA Synthetase in Complex with Compound AspS7HMDDA
Descriptor: (3~{S})-3-azanyl-4-[[(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxysulfonylamino]-4-oxidanylidene-butanoic acid, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2020-10-15
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.
Molecules, 25, 2020
7EA9
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Crystal Structure of human lysyl-tRNA synthetase Y145H mutant
Descriptor: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, Lysine--tRNA ligase
Authors:Wu, S, Hei, Z, Zheng, L, Zhou, J, Liu, Z, Wang, J, Fang, P.
Deposit date:2021-03-06
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analyses of a human lysyl-tRNA synthetase mutant associated with autosomal recessive nonsyndromic hearing impairment.
Biochem.Biophys.Res.Commun., 554, 2021

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PDB entries from 2024-05-22

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