9JM0
 
 | | retron Ec86-effector fiber | | Descriptor: | DNA (85-MER), NICOTINAMIDE, RNA (5'-R(P*CP*GP*UP*AP*AP*GP*GP*GP*UP*GP*CP*GP*CP*A)-3'), ... | | Authors: | Wang, Y.J, Guan, Z.Y, Wang, C, Zou, T.T. | | Deposit date: | 2024-09-20 | | Release date: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | DNA methylation activates retron Ec86 filaments for antiphage defense.
Cell Rep, 43, 2024
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1QAJ
 | | CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN | | Descriptor: | DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3'), REVERSE TRANSCRIPTASE | | Authors: | Najmudin, S, Cote, M, Sun, D, Yohannan, S, Montano, S.P, Gu, J, Georgiadis, M.M. | | Deposit date: | 1999-03-18 | | Release date: | 2000-04-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
J.Mol.Biol., 296, 2000
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3FSI
 | | Crystal structure of a trypanocidal 4,4'-Bis(imidazolinylamino)diphenylamine bound to DNA | | Descriptor: | 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', ACETATE ION, ... | | Authors: | Glass, L.S, Georgiadis, M.M, Goodwin, K.D. | | Deposit date: | 2009-01-09 | | Release date: | 2009-05-19 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA.
Biochemistry, 48, 2009
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1ZTT
 | | Netropsin bound to d(CTTAATTCGAATTAAG) in complex with MMLV RT catalytic fragment | | Descriptor: | 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', NETROPSIN, ... | | Authors: | Goodwin, K.D, Long, E.C, Georgiadis, M.M. | | Deposit date: | 2005-05-27 | | Release date: | 2005-08-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res., 33, 2005
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1ZTW
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8BGJ
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8C8J
 | | Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP | | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, ... | | Authors: | Nichols, C.E, Walpole, T.B, Baldwin, E. | | Deposit date: | 2023-01-20 | | Release date: | 2023-12-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
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4XO0
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4XPC
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4XPE
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8CS0
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9NLV
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9IOA
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9IOB
 | | Cryo-EM structure of the hexameric DRT9-ncRNA complex | | Descriptor: | RNA (177-MER), RNA-dependent DNA polymerase | | Authors: | Zhang, J.T, Song, X.Y, Xia, Y.S, Liu, Y.J, Jia, N. | | Deposit date: | 2024-07-08 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | Bacterial reverse transcriptase synthesizes long poly-A-rich cDNA for antiphage defense.
Science, 2025
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8QBL
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8QBK
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8QBM
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8GH6
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7R08
 | | Abortive infection DNA polymerase Abi-P2 | | Descriptor: | Reverse transcriptase | | Authors: | Gapinska, M.A, Figiel, M, Czarnocki Cieciura, M, Nowotny, M, Zajko, W. | | Deposit date: | 2022-02-01 | | Release date: | 2022-09-07 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7R06
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis | | Descriptor: | AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3') | | Authors: | Figiel, M, Nowotny, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W. | | Deposit date: | 2022-02-01 | | Release date: | 2022-09-07 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.27 Å) | | Cite: | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7R07
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis | | Descriptor: | AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), MAGNESIUM ION | | Authors: | Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M. | | Deposit date: | 2022-02-01 | | Release date: | 2022-09-07 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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8IBX
 | | Structure of R2 with 3'UTR and DNA in unwinding state | | Descriptor: | 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ... | | Authors: | Deng, P, Tan, S, Wang, J, Liu, J.J. | | Deposit date: | 2023-02-10 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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8IBW
 | | Structure of R2 with 3'UTR and DNA in binding state | | Descriptor: | 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ... | | Authors: | Deng, P, Tan, S, Wang, J, Liu, J.J. | | Deposit date: | 2023-02-10 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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8IBZ
 | | Structure of R2 with 5'ORF and 3'UTR | | Descriptor: | 5ORF-linker-3UTR, Reverse transcriptase-like protein, ZINC ION | | Authors: | Deng, P, Tan, S, Wang, J, Liu, J.J. | | Deposit date: | 2023-02-10 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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8IBY
 | | Structure of R2 with 5'ORF | | Descriptor: | 5'ORF RNA, Reverse transcriptase-like protein, ZINC ION | | Authors: | Deng, P, Tan, S, Wang, J, Liu, J.J. | | Deposit date: | 2023-02-10 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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