8QBL

Retron-Eco1 filament with inactive effector (E106A, 2 segments)

Summary for 8QBL

• Entry DOI: 10.2210/pdb8qbl/pdb
• EMDB information: 18314
• Descriptor: Retron Ec86 reverse transcriptase, Retron-Eco1-msr, Retron-Eco1-A2, ... (7 entities in total)
• Functional Keywords: retron, immune system, n-glycosidase, dna-rna-protein complex
• Biological source: Escherichia coli BL21(DE3); More
• Total number of polymer chains: 29
• Total formula weight: 762454.94

Authors

Carabias del Rey, A.,Montoya, G. (deposition date: 2023-08-24, release date: 2024-06-05, Last modification date: 2024-06-19)

• Primary citation: Carabias, A.,Camara-Wilpert, S.,Mestre, M.R.,Lopez-Mendez, B.,Hendriks, I.A.,Zhao, R.,Pape, T.,Fuglsang, A.,Luk, S.H.,Nielsen, M.L.,Pinilla-Redondo, R.,Montoya, G.; Retron-Eco1 assembles NAD + -hydrolyzing filaments that provide immunity against bacteriophages.; Mol.Cell, 84:2185-, 2024; PubMed: 38788717; DOI: 10.1016/j.molcel.2024.05.001

Experimental method

ELECTRON MICROSCOPY (2.66 Å)