1QAJ

CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN

Summary for 1QAJ

• Entry DOI: 10.2210/pdb1qaj/pdb
• Descriptor: DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3'), REVERSE TRANSCRIPTASE (3 entities in total)
• Functional Keywords: protein-dna complex, polymerase, reverse transcriptase, moloney murine leukemia virus, transferase-dna complex, transferase/dna
• Biological source: Moloney murine leukemia virus
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor (Potential). Matrix protein p15: Virion (Potential). Capsid protein p30: Virion (Potential). Nucleocapsid protein p10: Virion (Potential): P03355
• Total number of polymer chains: 4
• Total formula weight: 63548.74

Authors

Najmudin, S.,Cote, M.,Sun, D.,Yohannan, S.,Montano, S.P.,Gu, J.,Georgiadis, M.M. (deposition date: 1999-03-18, release date: 2000-04-02, Last modification date: 2024-02-14)

• Primary citation: Najmudin, S.,Cote, M.L.,Sun, D.,Yohannan, S.,Montano, S.P.,Gu, J.,Georgiadis, M.M.; Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.; J.Mol.Biol., 296:613-632, 2000; PubMed: 10669612; DOI: 10.1006/jmbi.1999.3477

Experimental method

X-RAY DIFFRACTION (2.3 Å)