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PDB: 252 results

8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
6T9L
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BU of 6t9l by Molmil
SAGA DUB module bound to a ubiqitinated nucleosome
Descriptor: Histone H2A, Histone H2B, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
5Z3O
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BU of 5z3o by Molmil
Structure of Snf2-nucleosome complex in ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ...
Authors:Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
Deposit date:2018-01-08
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
6IY3
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BU of 6iy3 by Molmil
Structure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), Histone H2A, ...
Authors:Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
Deposit date:2018-12-12
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
6ESF
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BU of 6esf by Molmil
Nucleosome : Class 1
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
8IHT
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BU of 8iht by Molmil
Rpd3S bound to the nucleosome
Descriptor: CALCIUM ION, Chromatin modification-related protein EAF3, DNA (164-MER), ...
Authors:Zhang, Y, Gang, C.
Deposit date:2023-02-23
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
8BZ1
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BU of 8bz1 by Molmil
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
6FQ5
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BU of 6fq5 by Molmil
Class 1 : canonical nucleosome
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2018-02-13
Release date:2018-04-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
4ZUX
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BU of 4zux by Molmil
SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Morgan, M, Wolberger, C.
Deposit date:2015-05-17
Release date:2016-02-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (3.82 Å)
Cite:Structural basis for histone H2B deubiquitination by the SAGA DUB module.
Science, 351, 2016
6NE3
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BU of 6ne3 by Molmil
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h bound at SHL-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (156-MER), Histone H2A type 1, ...
Authors:Armache, J.-P, Gamarra, N, Johnson, S.L, Leonard, J.D, Wu, S, Narlikar, G.N, Cheng, Y.
Deposit date:2018-12-16
Release date:2019-07-17
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome.
Elife, 8, 2019
6NOG
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BU of 6nog by Molmil
Poised-state Dot1L bound to the H2B-Ubiquitinated nucleosome
Descriptor: 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ...
Authors:Worden, E.J, Hoffmann, N.A, Wolberger, C.
Deposit date:2019-01-16
Release date:2019-02-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
6NN6
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BU of 6nn6 by Molmil
Structure of Dot1L-H2BK120ub nucleosome complex
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Anderson, C.J, Baird, M.R, Hsu, A, Barbour, E.H, Koyama, Y, Borgnia, M.J, McGinty, R.K.
Deposit date:2019-01-14
Release date:2019-02-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.
Cell Rep, 26, 2019
7YI4
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BU of 7yi4 by Molmil
Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state
Descriptor: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
Authors:Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
Deposit date:2022-07-14
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
7YI5
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BU of 7yi5 by Molmil
Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in loose state
Descriptor: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
Authors:Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
Deposit date:2022-07-14
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
5X0X
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BU of 5x0x by Molmil
Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome
Descriptor: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Li, M, Liu, X, Xia, X, Chen, Z, Li, X.
Deposit date:2017-01-23
Release date:2017-04-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
6KIW
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BU of 6kiw by Molmil
Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom)
Descriptor: DNA (144-MER), DNA (145-MER), Histone H2A, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
8CBQ
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BU of 8cbq by Molmil
structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3, ...
Authors:Koutna, E, Kouba, T, Novacek, J, Veverka, V.
Deposit date:2023-01-25
Release date:2023-09-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
7ZSA
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BU of 7zsa by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
6FQ6
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BU of 6fq6 by Molmil
Class 2 : distorted nucleosome
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2018-02-13
Release date:2018-04-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
6RYU
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BU of 6ryu by Molmil
Nucleosome-CHD4 complex structure (two CHD4 copies)
Descriptor: Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ...
Authors:Farnung, L, Ochmann, M, Cramer, P.
Deposit date:2019-06-12
Release date:2020-07-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-20
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
6KIV
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BU of 6kiv by Molmil
Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom)
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6R1T
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BU of 6r1t by Molmil
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome
Descriptor: DNA (147-MER), HISTONE H2A, Histone H2A, ...
Authors:Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A.
Deposit date:2019-03-15
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
6KIX
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BU of 6kix by Molmil
Cryo-EM structure of human MLL1-NCP complex, binding mode1
Descriptor: DNA (145-MER), GLUTAMINE, Histone H2A, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019

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