8BZ1

RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)

This is a non-PDB format compatible entry.

Summary for 8BZ1

• Entry DOI: 10.2210/pdb8bz1/pdb
• Related: 8BVW 8BYQ
• EMDB information: 16274 16331 16335 16336 16337 16338
• Descriptor: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, ... (26 entities in total)
• Functional Keywords: mammalian pic, +1 nucleosome, transcription initiation, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 28
• Total formula weight: 970850.93

Authors

Abril-Garrido, J.,Dienemann, C.,Grabbe, F.,Velychko, T.,Lidschreiber, M.,Wang, H.,Cramer, P. (deposition date: 2022-12-14, release date: 2023-05-03, Last modification date: 2023-06-14)

• Primary citation: Abril-Garrido, J.,Dienemann, C.,Grabbe, F.,Velychko, T.,Lidschreiber, M.,Wang, H.,Cramer, P.; Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.; Mol.Cell, 83:1798-, 2023; PubMed: 37148879; DOI: 10.1016/j.molcel.2023.04.011

Experimental method

ELECTRON MICROSCOPY (3.8 Å)