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PDB: 10 results
3LU9
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BU of 3lu9 by Molmil
Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Proteinase-activated receptor 1, ...
Authors:Gandhi, P.S, Chen, Z, Di Cera, E.
Deposit date:2010-02-17
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1.
J.Biol.Chem., 285, 2010
3HKI
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BU of 3hki by Molmil
Crystal structure of murine thrombin mutant W215A/E217A in complex with the extracellular fragment of human PAR1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 1, Thrombin heavy chain, ...
Authors:Gandhi, P.S, Page, M.J, Chen, Z, Bush-Pelc, L, Di Cera, E.
Deposit date:2009-05-23
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A.
J.Biol.Chem., 284, 2009
3BEF
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BU of 3bef by Molmil
Crystal structure of thrombin bound to the extracellular fragment of PAR1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 1, Prothrombin
Authors:Gandhi, P.S, Bah, A, Chen, Z, Mathews, F.S, Di Cera, E.
Deposit date:2007-11-17
Release date:2008-01-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural identification of the pathway of long-range communication in an allosteric enzyme.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3VW7
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BU of 3vw7 by Molmil
Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Proteinase-activated receptor 1, ...
Authors:Zhang, C, Srinivasan, Y, Arlow, D.H, Fung, J.J, Palmer, D, Zheng, Y, Green, H.F, Pandey, A, Dror, R.O, Shaw, D.E, Weis, W.I, Coughlin, S.R, Kobilka, B.K.
Deposit date:2012-08-07
Release date:2012-12-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-resolution crystal structure of human protease-activated receptor 1
Nature, 492, 2012
1NRR
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BU of 1nrr by Molmil
Crystallographic structures of Thrombin complexed with Thrombin receptor peptides: Existence of expected and novel binding modes
Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Proteinase-activated receptor 1, Thrombin heavy chain, ...
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
3HKJ
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BU of 3hkj by Molmil
Crystal structure of human thrombin mutant W215A/E217A in complex with the extracellular fragment of human PAR1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 1, Thrombin heavy chain, ...
Authors:Gandhi, P.S, Page, M.J, Chen, Z, Bush-Pelc, L, Di Cera, E.
Deposit date:2009-05-23
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A.
J.Biol.Chem., 284, 2009
1NRP
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BU of 1nrp by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NR'S
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRO
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BU of 1nro by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NRP
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRN
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BU of 1nrn by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NRS
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRQ
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BU of 1nrq by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE D-FPR'S
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994

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