4CH2
 
 | | Low-salt crystal structure of a thrombin-GpIbalpha peptide complex | | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | | Authors: | Lechtenberg, B.C, Freund, S.M.V, Huntington, J.A. | | Deposit date: | 2013-11-28 | | Release date: | 2013-12-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Gpibalpha Interacts Exclusively with Exosite II of Thrombin
J.Mol.Biol., 426, 2014
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1P9A
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4CH8
 | | High-salt crystal structure of a thrombin-GpIbalpha peptide complex | | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | | Authors: | Lechtenberg, B.C, Freund, S.M.V, Huntington, J.A. | | Deposit date: | 2013-11-29 | | Release date: | 2013-12-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Gpibalpha Interacts Exclusively with Exosite II of Thrombin
J.Mol.Biol., 426, 2014
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1M0Z
 | | Crystal Structure of the von Willebrand Factor Binding Domain of Glycoprotein Ib alpha | | Descriptor: | Glycoprotein Ib alpha | | Authors: | Huizinga, E.G, Tsuji, S, Romijn, R.A.P, Schiphorst, M.E, de Groot, P.G, Sixma, J.J, Gros, P. | | Deposit date: | 2002-06-16 | | Release date: | 2002-08-28 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
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3P72
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4C2A
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with R1306Q and I1309V Mutations in Complex with High Affinity GPIb alpha | | Descriptor: | ACETATE ION, CACODYLATE ION, CALCIUM ION, ... | | Authors: | Blenner, M.A, Dong, X, Springer, T.A. | | Deposit date: | 2013-08-16 | | Release date: | 2014-01-08 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.081 Å) | | Cite: | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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1OOK
 | | Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Human Alpha Thrombin, ... | | Authors: | Varughese, K.I, Celikel, R, Ruggeri, Z.M. | | Deposit date: | 2003-03-03 | | Release date: | 2003-07-22 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Modulation of alpha-thrombin function by distinct interactions with platelet
glycoprotein Ibalpha
Science, 301, 2003
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2BP3
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4YR6
 | | Fab fragment of 5G6 in complex with epitope peptide | | Descriptor: | ACE-LYS-LEU-ARG-GLY-VAL-LEU-GLN-GLY-HIS-LEU, GLYCEROL, heavy chain of 5G6, ... | | Authors: | Tao, Y, Mo, X, Li, R. | | Deposit date: | 2015-03-14 | | Release date: | 2016-03-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Structural basis for the specific inhibition of glycoprotein Ib alpha shedding by an inhibitory antibody.
Sci Rep, 6, 2016
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1SQ0
 | | Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution | | Descriptor: | Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin], Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II] | | Authors: | Dumas, J.J, Kumar, R, McDonagh, T, Sullivan, F, Stahl, M.L, Somers, W.S, Mosyak, L. | | Deposit date: | 2004-03-17 | | Release date: | 2004-04-13 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
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1P8V
 | | CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIISOPROPYL PHOSPHONATE, ... | | Authors: | Dumas, J.J, Kumar, R, Seehra, J, Somers, W.S, Mosyak, L. | | Deposit date: | 2003-05-07 | | Release date: | 2003-07-22 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of the GpIbalpha-Thrombin Complex Essential for Platelet Aggregation
Science, 301, 2003
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1QYY
 | | Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 2.8 Angstrom Resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PLATINUM (II) ION, Platelet glycoprotein Ib alpha chain, ... | | Authors: | Varughese, K.I, Ruggeri, Z.M, Celikel, R. | | Deposit date: | 2003-09-12 | | Release date: | 2004-03-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain.
Acta Crystallogr.,Sect.D, 60, 2004
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1GWB
 | | STRUCTURE OF GLYCOPROTEIN 1B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | | Authors: | Emsley, J, Uff, S, Clemetson, K.J.M, Clemetson, J.M, Harrison, T. | | Deposit date: | 2002-03-14 | | Release date: | 2003-02-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of the Platelet Glycoprotein Ib-Alpha N-Terminal Domain Reveals an Unmasking Mechanism of Receptor Activation
J.Biol.Chem., 277, 2002
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4C2B
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | | Authors: | Blenner, M.A, Dong, X, Springer, T.A. | | Deposit date: | 2013-08-16 | | Release date: | 2014-01-08 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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1U0N
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1M10
 | | Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain | | Descriptor: | Glycoprotein Ib alpha, von Willebrand Factor | | Authors: | Huizinga, E.G, Tsuji, S, Romijn, R.A.P, Schiphorst, M.E, de Groot, P.G, Sixma, J.J, Gros, P. | | Deposit date: | 2002-06-16 | | Release date: | 2002-08-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
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4MGX
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3PMH
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6XFQ
 | | Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor | | Descriptor: | Platelet glycoprotein Ib alpha chain, Snaclec agglucetin subunit alpha-1, Snaclec agglucetin subunit beta-2 | | Authors: | Wang, J, Gao, Y.X, Ke, J.Y, Zhu, Z.L, Niu, L.W. | | Deposit date: | 2020-06-16 | | Release date: | 2021-06-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor
To be published
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