4C2B
Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha
Summary for 4C2B
Entry DOI | 10.2210/pdb4c2b/pdb |
Related | 4C29 4C2A |
Descriptor | VON WILLEBRAND FACTOR, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, SULFATE ION, ... (6 entities in total) |
Functional Keywords | blood clotting |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P04275 Membrane; Single-pass type I membrane protein: P07359 |
Total number of polymer chains | 8 |
Total formula weight | 230057.11 |
Authors | Blenner, M.A.,Dong, X.,Springer, T.A. (deposition date: 2013-08-16, release date: 2014-01-08, Last modification date: 2023-12-20) |
Primary citation | Blenner, M.A.,Dong, X.,Springer, T.A. Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib J.Biol.Chem., 289:5565-, 2014 Cited by PubMed: 24391089DOI: 10.1074/JBC.M113.511220 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report