4CH2

Low-salt crystal structure of a thrombin-GpIbalpha peptide complex

Summary for 4CH2
Related4CH8
Related PRD IDPRD_000020
DescriptorTHROMBIN, LIGHT CHAIN, THROMBIN, HEAVY CHAIN, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, RESIDUES 287-300, ... (7 entities in total)
Functional Keywordshydrolase-peptide complex, hydrolase/peptide
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationSecreted, extracellular space: P00734 P07359
Membrane; Single-pass type I membrane protein: P00734
Total number of polymer chains6
Total formula weight72947.00
Authors
Lechtenberg, B.C.,Freund, S.M.V.,Huntington, J.A. (deposition date: 2013-11-28, release date: 2013-12-11, Last modification date: 2014-02-12)
Primary citationFreund, S.M.V.,Huntington, J.A.,Lechtenberg, B.C.
Gpibalpha Interacts Exclusively with Exosite II of Thrombin
J.Mol.Biol., 426:881-, 2014
PubMed: 24316004
DOI: 110.1016/J.JMB.2013.11.027
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation
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PDB entries from 2021-06-23