Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain

Summary for 1M10

Descriptorvon Willebrand Factor, Glycoprotein Ib alpha (2 entities in total)
Functional Keywordsleucine-rich repeat, hemostasis, dinucleotide binding fold, blood clotting
Biological sourceHomo sapiens (human)
Cellular locationSecreted P04275
Membrane; Single-pass type I membrane protein P07359
Total number of polymer chains2
Total molecular weight56066.29
Huizinga, E.G.,Tsuji, S.,Romijn, R.A.P.,Schiphorst, M.E.,de Groot, P.G.,Sixma, J.J.,Gros, P. (deposition date: 2002-06-16, release date: 2002-08-28, Last modification date: 2011-07-13)
Primary citation
Huizinga, E.G.,Tsuji, S.,Romijn, R.A.,Schiphorst, M.E.,de Groot, P.G.,Sixma, J.J.,Gros, P.
Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297:1176-1179, 2002
PubMed: 12183630 (PDB entries with the same primary citation)
DOI: 10.1126/science.107355
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28236 5.0% 5.8% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-23