1M10

Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	von Willebrand Factor	polymer	208	23731.4	1	UniProt (P04275) Pfam (PF00092) In PDB	Homo sapiens (human)
2	B	Glycoprotein Ib alpha	polymer	290	32334.8	1	UniProt (P07359) Pfam (PF01462) Pfam (PF13855) In PDB	Homo sapiens (human)	Platelet glycoprotein Ib alpha chain

Sequence modifications

A: 498 - 705 (UniProt: P04275)

PDB	External Database	Details
Gln 543	Arg 1306	engineered mutation

B: 1 - 290 (UniProt: P07359)

PDB	External Database	Details
Gln 21	Asn 37	engineered mutation
Gln 159	Asn 175	engineered mutation
Val 239	Met 255	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56066.3
All*	Total formula weight	56066.3

*Water molecules are not included.