3P72

structure of platelet Glycoprotein 1b alpha with a bound peptide inhibitor

Summary for 3P72

• Entry DOI: 10.2210/pdb3p72/pdb
• Related: 1GWB 1SQ0 1U0N
• Related PRD ID: PRD_000829
• Descriptor: Platelet glycoprotein Ib alpha chain, OS1 peptide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: leucine-rich repeat, coagulation, inhibitor, blood clotting-inhibitor complex, blood clotting/inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 31251.38

Authors

McEwan, P.A.,Andrews, R.K.,Emsley, J. (deposition date: 2010-10-12, release date: 2010-11-24, Last modification date: 2018-10-10)

• Primary citation: McEwan, P.A.,Andrews, R.K.,Emsley, J.; Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism.; Blood, 114:4883-4885, 2009; PubMed: 19726719; DOI: 10.1182/blood-2009-05-224170

Experimental method