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PDB: 487 results

6DM8
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BU of 6dm8 by Molmil
Understanding the Species Selectivity of Myeloid cell leukemia-1 (Mcl-1) inhibitors
Descriptor: 4-{8-chloro-11-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-1-oxo-7-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,5-dihydro-1H-[1,4]diazepino[1,2-a]indol-2(3H)-yl}-1-methyl-1H-indole-6-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog - MBP chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Zhao, B.
Deposit date:2018-06-04
Release date:2018-08-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Understanding the Species Selectivity of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors.
Biochemistry, 57, 2018
8AG0
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Crystal structure of mutant PRELID3a-TRIAP1 complex - R53E
Descriptor: Maltose/maltodextrin-binding periplasmic protein,TP53-regulated inhibitor of apoptosis 1, PRELI domain containing protein 3A, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Milara, X, Perez-Dorado, J.I, Matthews, S.J.
Deposit date:2022-07-18
Release date:2022-11-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An intermolecular hydrogen bonded network in the PRELID-TRIAP protein family plays a role in lipid sensing.
Biochim Biophys Acta Proteins Proteom, 1871, 2022
8GKH
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Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA
Descriptor: DNA (35-MER), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ...
Authors:Xu, P, Saito, M, Zhang, F.
Deposit date:2023-03-19
Release date:2023-07-05
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Fanzor is a eukaryotic programmable RNA-guided endonuclease.
Nature, 620, 2023
5I69
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BU of 5i69 by Molmil
MBP-MamC magnetite-interaction component mutant-D70A
Descriptor: Maltose-binding periplasmic protein,Tightly bound bacterial magnetic particle protein,Maltose-binding periplasmic protein, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Nudelman, H, Tercedor, C.V, Kolusheva, S, Gonzalez, T.P, Widdrat, M, Grimberg, N, Levi, H, Nelkenbaum, O, Davidove, G, Faivre, D, Jimenez-Lopez, C, Zarivach, R.
Deposit date:2016-02-16
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-function studies of the magnetite-biomineralizing magnetosome-associated protein MamC.
J.Struct.Biol., 194, 2016
4O2X
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BU of 4o2x by Molmil
Structure of a malarial protein
Descriptor: Maltose-binding periplasmic protein, ATP-dependent Clp protease adaptor protein ClpS containing protein chimeric construct
Authors:AhYoung, A.P, Koehl, A, Cascio, D, Egea, P.F.
Deposit date:2013-12-17
Release date:2014-12-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum.
Protein Sci., 25, 2016
3OB4
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BU of 3ob4 by Molmil
MBP-fusion protein of the major peanut allergen Ara h 2
Descriptor: CHLORIDE ION, Maltose ABC transporter periplasmic protein,Arah 2, SULFATE ION, ...
Authors:Mueller, G.A, Gosavi, R.A, Moon, A.F, London, R.E, Pedersen, L.C.
Deposit date:2010-08-06
Release date:2011-02-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.706 Å)
Cite:Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity.
Allergy, 66, 2011
3N95
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BU of 3n95 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2
Descriptor: Maltose binding protein-CRFR2 alpha extracellular domain, Urocortin-2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
Deposit date:2010-05-28
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
5ZNY
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BU of 5zny by Molmil
Structure of mDR3_DD-C363G with MBP tag
Descriptor: Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION
Authors:Yin, X, Jin, T.
Deposit date:2018-04-11
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
8AX5
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BU of 8ax5 by Molmil
Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029881
Descriptor: (1~{R},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3,5,7(30),20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ...
Authors:Southall, S.M, Watson, S.P.
Deposit date:2022-08-30
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode.
Acs Med.Chem.Lett., 13, 2022
3N96
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BU of 3n96 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1
Descriptor: Maltose binding protein-CRFR2 alpha, Urocortin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
Deposit date:2010-05-28
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3EHS
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BU of 3ehs by Molmil
Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1)
Descriptor: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, fusion protein of CRFR1 extracellular domain and MBP
Authors:Pioszak, A.A, Xu, H.E.
Deposit date:2008-09-14
Release date:2008-09-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
6DKS
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BU of 6dks by Molmil
Structure of the Rbpj-SHARP-DNA Repressor Complex
Descriptor: DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ...
Authors:Kovall, R.A, VanderWielen, B.D, Yuan, Z.
Deposit date:2018-05-30
Release date:2019-01-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site.
Cell Rep, 26, 2019
5EDU
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BU of 5edu by Molmil
Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
Descriptor: Maltose-binding periplasmic protein, Histone deacetylase 6 chimera, POTASSIUM ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-22
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
7VN6
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BU of 7vn6 by Molmil
Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning CGCACGTGCG
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*GP*CP*AP*CP*GP*TP*GP*CP*GP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ...
Authors:Nosaki, S, Tanokura, M, Miyakawa, T.
Deposit date:2021-10-10
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout.
Nat.Plants, 8, 2022
5V6Y
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BU of 5v6y by Molmil
Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant
Descriptor: ADM, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pioszak, A, Booe, J.
Deposit date:2017-03-17
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists.
Mol. Pharmacol., 93, 2018
5E7U
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BU of 5e7u by Molmil
MBP-MamC loop structure, a magnetite biomineralizing protein from Magnetospirillium magneticum AMB-1
Descriptor: Maltose-binding periplasmic protein,Tightly bound bacterial magnetic particle protein,Maltose-binding periplasmic protein, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Nudelman, H, Zarivach, R.
Deposit date:2015-10-13
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:MBP-MamC loop structure, a magnetite biomineralizing protein from Magnetospirillium magneticum AMB-1
To Be Published
6CXS
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BU of 6cxs by Molmil
Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine
Descriptor: 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, Beta-glucuronidase, Maltose/maltodextrin-binding periplasmic protein
Authors:Wallace, B.D, Redinbo, M.R.
Deposit date:2018-04-04
Release date:2019-04-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy.
Proc.Natl.Acad.Sci.USA, 2020
8XB3
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BU of 8xb3 by Molmil
Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter
Descriptor: 1-[(3-iodanylphenyl)methyl]guanidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2
Authors:Ji, W.M, Wu, J.X.
Deposit date:2023-12-05
Release date:2024-06-26
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Substrate binding and inhibition mechanism of norepinephrine transporter.
Nature, 633, 2024
5WVN
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BU of 5wvn by Molmil
Crystal structure of MBS-BaeS fusion protein
Descriptor: Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION
Authors:Wang, W, Zhang, Y, Ran, T, Xu, D.
Deposit date:2016-12-26
Release date:2018-01-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14
Proteins, 85, 2017
7XQC
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BU of 7xqc by Molmil
Crystal structure of N-terminal domain of Rv2908c fused with Maltose Binding Protein (MBP)
Descriptor: DI(HYDROXYETHYL)ETHER, Fusion protein of Maltose-binding periplasmic protein and RNA-binding protein KhpA
Authors:Thakur, K.G, Singh, A, Kapoor, S, Deep, A.
Deposit date:2022-05-07
Release date:2023-05-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of N-terminal domain of Rv2908c fused with Maltose Binding Protein (MBP)
To Be Published
6SLM
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BU of 6slm by Molmil
Crystal structure of full-length HPV31 E6 oncoprotein in complex with LXXLL peptide of ubiquitin ligase E6AP
Descriptor: GLYCEROL, Maltose/maltodextrin-binding periplasmic protein,Protein E6,Ubiquitin-protein ligase E3A, ZINC ION, ...
Authors:Conrady, M, Gogl, G, Cousido-Siah, A, Mitschler, A, Trave, G, Simon, C.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex Formation.
J.Virol., 95, 2020
7B01
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BU of 7b01 by Molmil
ADAMTS13-CUB12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Maltodextrin-binding protein,Maltodextrin-binding protein,Maltodextrin-binding protein,ADAMTS13 CUB12,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Kim, H.J, Emsley, J.
Deposit date:2020-11-18
Release date:2021-04-28
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of ADAMTS13 CUB domains reveals their role in global latency.
Sci Adv, 7, 2021
3MQ9
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BU of 3mq9 by Molmil
Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317 Fused to MBP
Descriptor: Bone marrow stromal antigen 2 fused to Maltose-binding periplasmic protein
Authors:Xiong, Y, Yang, H, Wang, J, Meng, W.
Deposit date:2010-04-27
Release date:2010-10-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insight into the mechanisms of enveloped virus tethering by tetherin.
Proc.Natl.Acad.Sci.USA, 107, 2010
4NUF
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BU of 4nuf by Molmil
Crystal Structure of SHP/EID1
Descriptor: EID1 peptide, Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct, ...
Authors:Zhi, X, Zhou, X.E, He, Y, Zechner, C, Suino-Powell, K.M, Kliewer, S.A, Melcher, K, Mangelsdorf, D.J, Xu, H.E.
Deposit date:2013-12-03
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into gene repression by the orphan nuclear receptor SHP.
Proc.Natl.Acad.Sci.USA, 111, 2014
1R6Z
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BU of 1r6z by Molmil
The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)
Descriptor: Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L.
Deposit date:2003-10-17
Release date:2004-01-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003

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