3EHS
Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1)
Summary for 3EHS
| Entry DOI | 10.2210/pdb3ehs/pdb |
| Related | 3EHT 3EHU |
| Related PRD ID | PRD_900001 |
| Descriptor | fusion protein of CRFR1 extracellular domain and MBP, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (3 entities in total) |
| Functional Keywords | g protein-coupled receptor, corticotropin releasing factor, scr fold, mbp fusion, extracellular domain, sugar transport, transport, cell membrane, glycoprotein, membrane, phosphoprotein, receptor, transducer, transmembrane, membrane protein |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 1 |
| Total formula weight | 52889.44 |
| Authors | Pioszak, A.A.,Xu, H.E. (deposition date: 2008-09-14, release date: 2008-09-30, Last modification date: 2023-08-30) |
| Primary citation | Pioszak, A.A.,Parker, N.R.,Suino-Powell, K.,Xu, H.E. Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1. J.Biol.Chem., 283:32900-32912, 2008 Cited by PubMed: 18801728DOI: 10.1074/jbc.M805749200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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